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Role of Interleukin-1β and Prostaglandin E2 in Prediction and Outcome of Apnea in Neonates

NCT06827197 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2025-02-14

No results posted yet for this study

Summary

Our thesis proposed that IL-1β may affect brainstem respiratory control via prostaglandin-dependant mechanism so we investigated the mediator roles of IL-1β and PGE2 levels in predicting apnea in pretertm newborn and their relation to clinical outcomes.

Conditions

  • Premature Newborns
  • Premature Newborns With Gestational Age 28 to 33 Weeks

Interventions

DIAGNOSTIC_TEST

Blood test

Blood samples were withdrawn from all the neonates under strict aseptic conditions and stored at -80°C for detecting PGE2 and IL-1β levels. PGE2 and IL-1β concentrations were measured using ELISA.

Sponsors & Collaborators

  • Benha University

    lead OTHER

Eligibility

Min Age
1 Day
Max Age
2 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2023-10-01
Completion
2023-10-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06827197 on ClinicalTrials.gov