Study to Assess Effectiveness and Safety of Zanubrutinib for Patients With Marginal Zone Lymphoma Treated in Italy Under the Named Patient Program (NPP)
NCT06823960 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 59
Last updated 2025-02-12
Summary
Observational, non-interventional, retrospective, multicentre study focusing on efficacy and safety of zanubrutinib in daily clinical practice in patients with relapsed/refractory (R/R) marginal zone lymphoma.
Conditions
- Marginal Zone Lymphoma(MZL)
Sponsors & Collaborators
-
IRCCS Azienda Ospedaliero-Universitaria di Bologna
lead OTHER
Principal Investigators
-
Pier Luigi Zinzani, MD · IRCCS Azienda Ospedaliero-Universitaria di Bologna
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-12-09
- Primary Completion
- 2025-06-30
- Completion
- 2025-06-30
Countries
- Italy
Study Locations
More Related Trials
-
Zanubrutinib-based Maintenance Therapy of Newly Diagnosed DLBCL With Initial Remission
NCT06669143 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Zanubrutinib+Lenalidomide+R-ICE in Relapsed/Refractory DLBCL
NCT06033820 ·Status: RECRUITING ·Phase: PHASE2
-
Zanubrutinib in Combination With Obinutuzumab (ZO) for Newly Diagnosed Follicular Lymphoma
NCT06553352 ·Status: RECRUITING ·Phase: PHASE2
-
GZL Sequential CD19/CD22 CAR-T in Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
NCT05797948 ·Status: UNKNOWN ·Phase: NA
-
Obinutuzumab in Combination With Lenalidomide in Relapsed or Refractory Marginal Zone Lymphoma
NCT05846750 ·Status: RECRUITING ·Phase: PHASE2
-
Zanubrutinib-rituximab(ZR) in Patients With Newly Diagnosed Untreated Mantle Cell Lymphoma
NCT05504603 ·Status: UNKNOWN ·Phase: PHASE2
-
Linperlisib Combination With Obinutuzumab Frontline Treatment of Marginal Zone Lymphoma Patients (MZL)
NCT06592170 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Optimize Study - Orelabrutinib Combined With BR/G in Untreated Marginal Zone Lymphoma (MZL)
NCT06504940 ·Status: RECRUITING ·Phase: PHASE2
-
Study With Mosunetuzumab and Zanubrutinib in R/R Follicular Lymphoma Patients
NCT06492837 ·Status: RECRUITING ·Phase: PHASE2
-
This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma
NCT06427213 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Zanubrutinib Plus Rituximab for Patients With Indolent Mantle Cell Lymphoma
NCT05635162 ·Status: RECRUITING ·Phase: PHASE2
-
Zanubrutinib, Obinutuzumab, and Lenalidomide (ZGR) in the Treatment of Newly Diagnosed Splenic B-cell Lymphoma With Prominent Nucleoli (SBLPN): A Prospective, Open-label, Single-arm Clinical Trial
NCT07165769 ·Status: RECRUITING ·Phase: PHASE2
-
Obinutuzumab, Zanubrutinib, and Lenalidomide Followed Short-Cycle of Obinutuzumab and Cytarabine in Newly Diagnosed Mantle Cell Lymphoma
NCT06504199 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
MZL-IPI Risk-adapted Targeted Therapy in Untreated MZL
NCT06793189 ·Status: RECRUITING ·Phase: PHASE2
-
Zanubrutinib, Rituximab, and Lenalidomide in the First-Line Treatment of Marginal Zone Lymphoma
NCT07299331 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Zanubrutinib and Lenalidomide as Maintenance Therapy in DLBCL
NCT06503263 ·Status: RECRUITING ·Phase: PHASE2
-
Zanubrutinib, Obinutuzumab and Lenalidomide (ZGR) in High-risk Treatment-naive Patients with Follicular Lymphoma (FL)
NCT06549335 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Prospective Clinical Study of Orelabrutinib in Combination With Rituximab (OR) for Primary Marginal Zone Lymphoma (MZL) That Failed or Not Suitable for Local Therapy
NCT06478472 ·Status: RECRUITING ·Phase: NA
-
Zanubrutinib in Maintenance Therapy of DLBCL Patients With Initial Remission
NCT05596097 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL)
NCT03206970 ·Status: COMPLETED ·Phase: PHASE2
-
Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed/Refractory Marginal Zone Lymphoma
NCT01980628 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation
NCT04002297 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study of Acalabrutinib and Tafasitamab in MZL Patients
NCT04646395 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of the Zanubrutinib Given in Combination With Bendamustine and Rituximab in (Elderly or TP53 Alterations or Chemotherapy Intolerance) Patients With Newly Diagnosed Mantle Cell Lymphoma
NCT06136351 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Zanubrutinib in Combination With Polatuzumab Vedotin, Bendamustine and Rituximab in the Treatment of Relapsed/Refractory Diffuse Large B-cell Lymphoma
NCT06554600 ·Status: RECRUITING ·Phase: PHASE2