Trial Outcomes & Findings for RCT-Consumer Perceptions of Cannabidiol (CBD) Health Claims (NCT NCT06800066)
NCT ID: NCT06800066
Last Updated: 2026-08-28
Results Overview
The primary outcome is purchase of a CBD product. The percent of participants who purchase at least one CBD product in each group (CBD ads vs non-CBD ads) will be reported.
COMPLETED
NA
460 participants
Hour 1 on day 1
2026-08-28
Participant Flow
Participant milestones
| Measure |
Control Arm (Non-CBD Ads)
In the control condition, the Mini-Mart will display 18 advertisements that are public service announcement (PSA) - type messages. These ads are not related to any products (CBD or non-CBD products) available in the Mini-Mart.
Purchase Behavior - (Non-CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
|
Experimental Arm (CBD Ads)
In the experimental condition, the Mini-Mart will display 18 different advertisements for CBD and 1 display box for a CBD product.
Purchase Behavior - (CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
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|---|---|---|
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Overall Study
STARTED
|
230
|
230
|
|
Overall Study
COMPLETED
|
230
|
230
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
RCT-Consumer Perceptions of Cannabidiol (CBD) Health Claims
Baseline characteristics by cohort
| Measure |
Total
n=460 Participants
Total of all reporting groups
|
Control Arm (Non-CBD Ads)
n=230 Participants
In the control condition, the Mini-Mart will display 18 advertisements that are public service announcement (PSA) - type messages. These ads are not related to any products (CBD or non-CBD products) available in the Mini-Mart.
Purchase Behavior - (Non-CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
|
Experimental Arm (CBD Ads)
n=230 Participants
In the experimental condition, the Mini-Mart will display 18 different advertisements for CBD and 1 display box for a CBD product.
Purchase Behavior - (CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
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|---|---|---|---|
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Age, Continuous
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44.0 years
STANDARD_DEVIATION 16.4 • n=80 Participants
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43.7 years
STANDARD_DEVIATION 15.5 • n=31 Participants
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44.3 years
STANDARD_DEVIATION 17.3 • n=49 Participants
|
|
Sex/Gender, Customized
male
|
141 participants
n=80 Participants
|
69 participants
n=31 Participants
|
72 participants
n=49 Participants
|
|
Sex/Gender, Customized
female
|
317 participants
n=80 Participants
|
160 participants
n=31 Participants
|
157 participants
n=49 Participants
|
|
Sex/Gender, Customized
unknown
|
2 participants
n=80 Participants
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1 participants
n=31 Participants
|
1 participants
n=49 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
34 Participants
n=80 Participants
|
23 Participants
n=31 Participants
|
11 Participants
n=49 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
421 Participants
n=80 Participants
|
203 Participants
n=31 Participants
|
218 Participants
n=49 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
5 Participants
n=80 Participants
|
4 Participants
n=31 Participants
|
1 Participants
n=49 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
8 Participants
n=80 Participants
|
3 Participants
n=31 Participants
|
5 Participants
n=49 Participants
|
|
Race (NIH/OMB)
Asian
|
36 Participants
n=80 Participants
|
16 Participants
n=31 Participants
|
20 Participants
n=49 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=80 Participants
|
0 Participants
n=31 Participants
|
0 Participants
n=49 Participants
|
|
Race (NIH/OMB)
Black or African American
|
66 Participants
n=80 Participants
|
36 Participants
n=31 Participants
|
30 Participants
n=49 Participants
|
|
Race (NIH/OMB)
White
|
304 Participants
n=80 Participants
|
147 Participants
n=31 Participants
|
157 Participants
n=49 Participants
|
|
Race (NIH/OMB)
More than one race
|
19 Participants
n=80 Participants
|
9 Participants
n=31 Participants
|
10 Participants
n=49 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
27 Participants
n=80 Participants
|
19 Participants
n=31 Participants
|
8 Participants
n=49 Participants
|
PRIMARY outcome
Timeframe: Hour 1 on day 1The primary outcome is purchase of a CBD product. The percent of participants who purchase at least one CBD product in each group (CBD ads vs non-CBD ads) will be reported.
Outcome measures
| Measure |
Control Arm (Non-CBD Ads)
n=230 Participants
In the control condition, the Mini-Mart will display 18 advertisements that are public service announcement (PSA) - type messages. These ads are not related to any products (CBD or non-CBD products) available in the Mini-Mart.
Purchase Behavior - (Non-CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
|
Experimental Arm (CBD Ads)
n=230 Participants
In the experimental condition, the Mini-Mart will display 18 different advertisements for CBD and 1 display box for a CBD product.
Purchase Behavior - (CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
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|---|---|---|
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Purchase of at Least One CBD Product
|
163 Participants
|
171 Participants
|
SECONDARY outcome
Timeframe: Hour 1 on day 1Population: One participant did not answer this question
Twelve items will measure participants' perceptions about the possible benefits of CBD - the mean number of selected benefits for each group (CBD ads vs non-CBD ads). Reporting the mean number of benefits selected (out of 12).
Outcome measures
| Measure |
Control Arm (Non-CBD Ads)
n=229 Participants
In the control condition, the Mini-Mart will display 18 advertisements that are public service announcement (PSA) - type messages. These ads are not related to any products (CBD or non-CBD products) available in the Mini-Mart.
Purchase Behavior - (Non-CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
|
Experimental Arm (CBD Ads)
n=230 Participants
In the experimental condition, the Mini-Mart will display 18 different advertisements for CBD and 1 display box for a CBD product.
Purchase Behavior - (CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
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|---|---|---|
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Number of Benefits of CBD
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5.6 number of benefits
Standard Deviation 2.8
|
5.7 number of benefits
Standard Deviation 2.7
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SECONDARY outcome
Timeframe: Hour 1 on day 1Population: 4 people did not answer this question (Control Arm) and 1 person did not answer question (Experimental Arm)
During the post shopping task survey, the Participant will randomly view 1 (out of 11) CBD-labeled products that were available to purchase in the Mini-Mart. The participant will respond to a one-item measure that assesses the extent to which the participant perceives that the CBD product is safe to consume. Response options are on a 1 to 5 scale, with higher scores representing more perceived safety (i.e. 1- Not at all safe to 5- Extremely safe). The overall mean score and response option frequencies for all products combined for each group (CBD ads vs non-CBD ads) will be reported.
Outcome measures
| Measure |
Control Arm (Non-CBD Ads)
n=226 Participants
In the control condition, the Mini-Mart will display 18 advertisements that are public service announcement (PSA) - type messages. These ads are not related to any products (CBD or non-CBD products) available in the Mini-Mart.
Purchase Behavior - (Non-CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
|
Experimental Arm (CBD Ads)
n=229 Participants
In the experimental condition, the Mini-Mart will display 18 different advertisements for CBD and 1 display box for a CBD product.
Purchase Behavior - (CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
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|---|---|---|
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Perceived Product Safety
|
3.0 score on a scale
Standard Deviation 0.8
|
3.0 score on a scale
Standard Deviation 0.7
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SECONDARY outcome
Timeframe: Hour 1 on day 1Population: Questions were only asked of those who had never used CBD (never users) and those who had used longer than a year ago (ever users).
One item will be used to measure willingness to try CBD. Response items are on a 1 to 5 scale, with higher scores representing more likelihood to try CBD (i.e. 1- Extremely Unlikely to 5- Extremely Likely). The mean score and response option frequencies of each group (CBD ads vs non CBD ads) will be reported.
Outcome measures
| Measure |
Control Arm (Non-CBD Ads)
n=149 Participants
In the control condition, the Mini-Mart will display 18 advertisements that are public service announcement (PSA) - type messages. These ads are not related to any products (CBD or non-CBD products) available in the Mini-Mart.
Purchase Behavior - (Non-CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
|
Experimental Arm (CBD Ads)
n=154 Participants
In the experimental condition, the Mini-Mart will display 18 different advertisements for CBD and 1 display box for a CBD product.
Purchase Behavior - (CBD ads): Participants will complete 1 shopping visit and will be randomly assigned to one of 2 conditions: 1) non-CBD advertising (control condition) or 2) CBD advertising (experimental condition). Each condition will have approximately 20 advertisements. In each condition, the Participant will be asked to purchase 3 products.
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|---|---|---|
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Willingness to Try CBD (Non-current CBD Users)
|
3.7 score on a scale
Standard Deviation 1.3
|
3.8 score on a scale
Standard Deviation 1.3
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OTHER_PRE_SPECIFIED outcome
Timeframe: Hour 1 on day 1Eleven items will measure participants' perceptions about the possible outcomes of CBD. Response items are on a 1 to 4 scale, with higher scores representing more agreement with the stated effect (i.e. 1- Strongly disagree to 4- Strongly agree). The mean score and response option frequencies of each item for each group (CBD ads vs non-CBD ads) will be reported.
Outcome measures
Outcome data not reported
OTHER_PRE_SPECIFIED outcome
Timeframe: Hour 1 on day 1During the post shopping task survey, the Participant will randomly view 1 (out of 11) CBD-labeled products that were available to purchase in the Mini-Mart. The Participant will respond to a one-item measure that assesses the extent to which the product is appealing to them. Response options are on a 1 to 5 scale, with higher scores representing more appeal (i.e. 1- Not at all appealing to 5- Extremely appealing). The overall mean score and response option frequencies for all products combined for each group (CBD ads vs non-CBD ads) will be reported.
Outcome measures
Outcome data not reported
Adverse Events
Control Arm (Non-CBD Ads)
Experimental Arm (CBD Ads)
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Kimberly Wagoner, DrPH, MPH
Wake Forest University Health Sciences
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place