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Therapeutic Effect of Vitamin C Supplementation in Patients With Ovarian Aging

NCT06794060 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 354

Last updated 2025-06-26

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if Vitamin C works to improve ovarian reserve in women with ovarian aging. It will also learn about the safety of Vitamin C. The main questions it aims to answer are:

* Does Vitamin C supplementation improve the ovarian reserve prediction score?
* What medical problems do participants have when taking Vitamin C supplementation?

Researchers will compare Vitamin C to a placebo (a look-alike substance that contains no drug) to see if drug Vitamin C works to improve ovarian reserve in women with ovarian aging. Participants will:

* Take Vitamin C or a placebo every day for 12 months
* Visit the clinic once every 4 weeks for follow-up and drug distribution.
* Return the Vitamin C box at each visit.
* Report any adverse effects of treatment to the doctor.
* Fill out a questionnaire at each visit.
* After 6 months and 12 months of intervention, take blood test and ultrasonic examination.

Conditions

  • Premature Ovarian Insufficiency
  • Ovarian Reserve Function

Interventions

DIETARY_SUPPLEMENT

Vitamin C (Ascorbic Acid)

Participants swallow synthetic vitamin C tablets 500mg with water, twice a day.

DIETARY_SUPPLEMENT

Vitamin C (Ascorbic Acid)

Participants swallow naturral vitamin C tablets 500mg with water, twice a day.

OTHER

Placebo

Participants swallow tablets with the same texture, flavor, and appearance as the experimental group 500mg with water, twice a day.

Sponsors & Collaborators

  • Peking University Third Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-02
Primary Completion
2025-12-31
Completion
2027-08-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06794060 on ClinicalTrials.gov