Development of Organoids From Primary Colorectal Tumors and Synchronous Liver Metastases
NCT06787625 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2025-01-22
Summary
Pilot feasibility study for the development of organoids from primary colorectal tumors and synchronous liver metastases, to prepare organoids from primary colorectal tumors and synchronous liver metastases. The organoids will allow us to study the function of genes targeted by the activity of the NF-Y/p53 complex.
Conditions
- Colo-rectal Cancer
Sponsors & Collaborators
-
Regina Elena Cancer Institute
lead OTHER
Principal Investigators
-
Giulia Piaggio, Biologist · IRCCS National Cancer Institute
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-05-25
- Primary Completion
- 2028-01-25
- Completion
- 2028-05-25
Countries
- Italy
Study Locations
More Related Trials
-
Immunophenotyping of Metastases From Colorectal Cancer
NCT03604926 ·Status: COMPLETED
-
Metastatic Lymph Node Distribution in the Ileum Mesentery of Cecal and Proximal Ascending Colon Cancer
NCT07149623 ·Status: NOT_YET_RECRUITING
-
L-BLP25 in Patients With Colorectal Carcinoma After Curative Resection of Hepatic Metastases
NCT01462513 ·Status: COMPLETED ·Phase: PHASE2
-
Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy
NCT03364621 ·Status: ACTIVE_NOT_RECRUITING
-
Patient-tailored Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Colorectal Peritoneal Metastases (OrganoHIPEC)
NCT06057298 ·Status: UNKNOWN ·Phase: NA
-
Study of Immune Response and Liver Damage Induced by Chemotherapy for Liver Metastases of Colorectal Cancer
NCT01673607 ·Status: UNKNOWN ·Phase: PHASE2
-
Contribution of Oncovascular Surgery in the Treatment of Gynecological Advanced Malignant Diseases.
NCT07267780 ·Status: NOT_YET_RECRUITING
-
Identify the Clinical Significance and Potential Implications of Peritoneal Washing Cytology (PWC) in Patients With Pancreatic Cancer
NCT01127815 ·Status: UNKNOWN
-
Simultaneous Versus Staged Resection for Initially Resectable Synchronous Rectal Cancer Liver-limited Metastasis
NCT00677586 ·Status: COMPLETED ·Phase: NA
-
Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype
NCT06753136 ·Status: RECRUITING ·Phase: NA
-
Total/Subtotal Colectomy in Ovarian Cancer
NCT02595021 ·Status: UNKNOWN ·Phase: PHASE2
-
Gene Expression Profile of Resected Pancreatic and Ampullary Adenocarcinoma at Favorable Prognosis
NCT05754788 ·Status: UNKNOWN
-
Proactive Management of Endoperitoneal Spread in Colonic Cancer
NCT02974556 ·Status: UNKNOWN ·Phase: PHASE3
-
Analysis of Oncogenes in Intrahepatic Cholangiocarcinoma or Mixed Hepatocellular-Cholangiocarcinoma in Tumor Tissue Samples
NCT02762721 ·Status: COMPLETED
-
Elevated Platelet Count as Prognostic Factor in Colorectal Cancer With Synchronous Liver Metastases
NCT03717519 ·Status: COMPLETED
-
Radiomics of Colorectal Liver Metastases: Identification of New Prognostic Biomarkers.
NCT06779734 ·Status: COMPLETED
-
Surgical Treatment of Pancreatic RCC Metastases
NCT03670992 ·Status: COMPLETED
-
Exhaustive Genetic and Immunological Characterization of Colon, Kidney and Liver Tumors
NCT03149523 ·Status: UNKNOWN
-
Second Look Laparoscopy in Colorectal Cancer
NCT01628211 ·Status: UNKNOWN ·Phase: PHASE2
-
Molecular Characterisation of Colorectal Cancer Peritoneal Metastases
NCT05513716 ·Status: RECRUITING
-
Next Generation Sequencing in Intrahepatic Cholangiocarcinoma
NCT02184871 ·Status: UNKNOWN
-
Detection of CTCs in Patients Undergoing Surgery for Stage IV Colorectal Cancer
NCT01722903 ·Status: COMPLETED
-
Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers
NCT06967961 ·Status: RECRUITING ·Phase: NA
-
Impact of Preoperative Chemotherapy on Complications and Regeneration After Resection of Colorectal Liver Metastases
NCT00779272 ·Status: COMPLETED
-
Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases
NCT04616495 ·Status: RECRUITING