SCRT(Short Course Radiotherapy) Combined With CAPOX Plus QL1706 for Rectal Cancer Liver Metastases
NCT06787183 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 42
Last updated 2026-03-03
Summary
To enhance the treatment efficacy of rectal cancer liver metastasis through a multidisciplinary approach of radiotherapy, immunotherapy, and chemotherapy, and to provide a new direction for the combination treatment strategy.
Conditions
- Locally Advanced Rectal Cancer With Liver Metastases
Interventions
- DRUG
-
130mg/m2, d1, q3w, 2 cycles
- DRUG
-
QL1706
5.0 mg/kg, q3w
- RADIATION
-
Short course radiotherapy
CTV 25Gy/5Fx.
- DRUG
-
1000mg/m2, d1-14,bid, q3w, 2 cycles.
Sponsors & Collaborators
-
Fujian Cancer Hospital
lead OTHER_GOV
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-01
- Primary Completion
- 2026-12-01
- Completion
- 2029-12-01
Countries
- China
Study Locations
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