Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment
NCT06784167 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 45
Last updated 2025-09-15
Summary
This study evaluates immune responses after CAR-T therapy to find out if CAR-T therapy reduces the effectiveness of the vaccines (vaccine immunity) against diseases such as measles, mumps and rubella, among others in patients with multiple myeloma and non-Hodgkin lymphoma.
Conditions
- Chronic Lymphocytic Leukemia
- Diffuse Large B-Cell Lymphoma
- Follicular Lymphoma
- Mantle Cell Lymphoma
- Multiple Myeloma
- Primary Mediastinal Large B-Cell Lymphoma
- Small Lymphocytic Lymphoma
Interventions
- OTHER
-
Non-Interventional Study
Non-interventional study
Sponsors & Collaborators
-
Oregon Health and Science University
collaborator OTHER -
OHSU Knight Cancer Institute
lead OTHER
Principal Investigators
-
Amrita Desai · OHSU Knight Cancer Institute
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-03-10
- Primary Completion
- 2027-01-11
- Completion
- 2027-04-12
Countries
- United States
Study Locations
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