Clinical Outcomes of Use of Olaparib in Castration Resistant Prostate Cancer
NCT06783127 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 3000
Last updated 2025-02-11
Summary
This is an observational, retrospective/prospective, multicenter study designed to define, overall survival, clinical outcomes and predictive/prognostic factors of a consecutive population of mCRPC patients treated with olaparib in clinical practice.
Conditions
- Prostate Cancer
- Castrate Resistant Prostate Cancer
- BRCA Mutation
Interventions
- DRUG
-
Olaparib given according the clinical practice to BRCA positive mCRPC patients
Sponsors & Collaborators
-
Santa Chiara Hospital
lead OTHER
Eligibility
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-01-01
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
- FDA Drug
- Yes
Countries
- Italy
Study Locations
More Related Trials
-
Observational Registry of Treatment Patterns in Castrate-resistant Prostate Cancer (CRPC) Patients
NCT01076751 ·Status: TERMINATED
-
Study of Lanreotide in Non Metastatic Castration-resistant Prostate Cancer Patients
NCT01313273 ·Status: TERMINATED ·Phase: PHASE3
-
Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis
NCT03047135 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer
NCT03732820 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Observational Cohort Study of Patients With Castration-Resistant Prostate Cancer (CRPC)
NCT02380274 ·Status: COMPLETED
-
Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations
NCT05457257 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer
NCT03516812 ·Status: COMPLETED ·Phase: PHASE2
-
Metastasis-directed Therapy for Oligorecurrent Prostate Cancer
NCT05352178 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT03431350 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
NCT06136650 ·Status: RECRUITING ·Phase: PHASE3
-
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort)
NCT05171816 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Safety and Tolerability of ODM-201 in Castrate Resistant Prostate Cancer; Extension Study to Study 3104001
NCT01429064 ·Status: COMPLETED ·Phase: PHASE2
-
Castration-resistant Prostate Cancer and Intra-prostatic Hormonal Status
NCT03014973 ·Status: WITHDRAWN ·Phase: NA
-
Real-life Experience in Brazil in Patients With Castration-resistant Prostate Cancer Treated With Olaparib+Abiraterone
NCT06457854 ·Status: WITHDRAWN
-
Utilizing A Genomic Sig for "BRCAness" to Eval the Efficacy of Satraplatin in Men With Met. Castration Resistant Prostate Ca
NCT01289067 ·Status: COMPLETED ·Phase: PHASE2
-
177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia
NCT07025512 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Multi-centre Study to Assess the Safety, Tolerability, and Pharmacokinetics of Capivasertib (AZD5363) in Combination With Novel Agents in Patients With Metastatic Prostate Cancer
NCT04087174 ·Status: COMPLETED ·Phase: PHASE1
-
Addition of Opaganib to Androgen Antagonists in Patients With mCRPC
NCT04207255 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Pharmacokinetics of ODM-204 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT02344017 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
FPI-2265 (225Ac-PSMA-I&T) and Olaparib for Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
NCT06909825 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Cisplatin in Castration Resistant Prostate Cancer
NCT03275857 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Pharmacogenetic Study in Castration-resistant Prostate Cancer Patients Treated With Abiraterone Acetate
NCT01858441 ·Status: COMPLETED ·Phase: NA
-
Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)
NCT06353386 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
177Lu-PSMA-617 Therapy and Olaparib in Patients With Metastatic Castration Resistant Prostate Cancer
NCT03874884 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Observe Demography and the Outcome of Prostate Cancer Patients Treated With 6-month Triptorelin Formulation in Italy
NCT05759273 ·Status: COMPLETED