Reproductive Health Outcomes in Young Patients with Ovarian Cancer After Surgical Treatment: a Retrospective Study
NCT06777147 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2025-01-15
Summary
Ovarian cancer (OC) is the second commonest gynecological cancer with an overall incidence of 1.4% , associated with high mortality rate , There are three major types of ovarian cancers: epithelial ovarian carcinomas, germ cell tumors, and stromal cell tumors .
Ovarian cancer directly affects fertility, as treatment consists of surgical removal of the reproductive system and/or exposure to gonadotoxic agents. However, patients in early stages who meet established criteria can be treated with fertility-sparing surgeries and reach equivalent oncological results to those of traditional treatments. Fertility preservation techniques such as cryopreservation of oocytes, embryos and ovarian tissue may also be offered in some situations.
Ovarian cancer (OC) has a high mortality rate and usually presents late in advanced stage, which poses challenges to management. Better understanding of the disease biology and application of radical surgery (RS) to achieve no visible residual tumor, alongside with chemotherapy, may lead to longer survival amongst these patients. Our purpose is to find out the fertility and survival rates of women with Overian Cancer in reproductive women who underwent surgical intervention. Radical Surgery for Overian cancer is one of the most challenging procedures in gynecologic oncology surgery.
Conditions
Sponsors & Collaborators
-
Assiut University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-01-31
- Primary Completion
- 2026-01-31
- Completion
- 2026-04-30
More Related Trials
-
Why Are Fertility Preservation Patients Not Coming Back?
NCT05223764 ·Status: COMPLETED
-
Determinants of Age-Related Treatment Effectiveness in Ovarian Cancer
NCT02973750 ·Status: COMPLETED
-
Microscopic Peritoneal Metastases After Complete Macroscopic Cytoreductive Surgery for Epithelial Ovarian Cancer
NCT03754569 ·Status: COMPLETED ·Phase: NA
-
Sexual Functioning After Primary Treatment of Ovarian Cancer
NCT00596544 ·Status: TERMINATED
-
Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer
NCT06360471 ·Status: RECRUITING
-
Assessing Reproductive Outcomes in Young Female Cancer Survivors Through a National Fertility Preservation Registry
NCT01843140 ·Status: ACTIVE_NOT_RECRUITING
-
Transcriptional Map of Ovarian Cancer at the Single Cell Level
NCT05030805 ·Status: RECRUITING
-
A New Fast DWI-based MR Protocol for Surveillance in Patients With a High Risk of Ovarian Cancer Recurrence During PARP-inhibitors Maintenance to Enhance Secondary Cytoreduction Results
NCT06541171 ·Status: NOT_YET_RECRUITING
-
Ovarian Reserve Testing in Female Young Adult Cancer Survivors
NCT01421095 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Hyperthermic Intraoperative Intraperitoneal Chemotherapy of Recurrent Ovarian Cancer - A Feasibility Study
NCT00968799 ·Status: TERMINATED ·Phase: NA
-
Optimize the Support of Patients in Pelvic Onco-gynecology Through Adapted Support Care in the Post-cancer Period. AFTERGYN Pilot Phase
NCT05731661 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Why do Oral Contraceptives Prevent Ovarian Cancer?
NCT02155777 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Improving Quality of Care for Patients With Recurrent Ovarian Cancer
NCT02809339 ·Status: UNKNOWN
-
Secondary Cytoreductive Surgery in Platinum-resistant Recurrent Ovarian Cancers
NCT04795596 ·Status: WITHDRAWN ·Phase: PHASE2/PHASE3
-
Survival Data and Characteristics of Finisterian Patients Treated With PARP Inhibitors for Ovarian Cancer Between 2014 and 2019.
NCT04573933 ·Status: COMPLETED
-
The Efficacy of Hyperthermic Intraperitoneal Chemotherapy to Ovarian Cancer Patients With Homologous Recombination Repair Defect and Residual: a Prospective Cohort Study
NCT05265117 ·Status: UNKNOWN
-
An INternational Frontline Ovarian Cancer Real World Management Study
NCT04460768 ·Status: COMPLETED
-
Survival Effect of Hepato-celiac Lymphadenectomy In Primary or Relapsed Ovarian Cancer
NCT05236686 ·Status: RECRUITING ·Phase: NA
-
Molecular Classification in Relation to Prevention of Endometrial Cancer Recurrence and Lifestyle Factors
NCT06680791 ·Status: RECRUITING
-
Observational, Bi-directional (Prospective and Retrospective) Study for Patients With Newly Diagnosed Ovarian Cancer Stages IA to IVB, or Persistent or Recurrent Disease From January 2021; Irrespective of Histology
NCT07167433 ·Status: RECRUITING
-
Ovarian Cancer Risk Estimation in Patients With Pelvic Mass
NCT00987649 ·Status: COMPLETED
-
Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
NCT01372787 ·Status: UNKNOWN
-
DOD Long-Term Survivors of Ovarian Cancer
NCT02321735 ·Status: UNKNOWN ·Phase: NA
-
Quality-of-Life Study of Patients With Previously Treated Ovarian Cancer
NCT00003794 ·Status: TERMINATED
-
Intra-peritoneal Chemotherapy in Ovarian Cancer
NCT02861872 ·Status: UNKNOWN