Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement

NCT06768762 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 336

Last updated 2026-05-05

No results posted yet for this study

Summary

The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.

Conditions

  • Knee Replacement

Interventions

BEHAVIORAL

Phone Coaching

Participants will receive 11 coaching calls with a health coach. Calls will occur weekly during the first month, twice/month during months 2-3, and once/month during months 4-6. Each call is expected to last 10-15 minutes.

BEHAVIORAL

Progress reports to providers

Progress reports on physical activity and program adherence will be sent to participants providers at 3 and 6 months.

BEHAVIORAL

'Hear from Others' Videos

Participants will receive monthly 'Hear From Others' videos. The videos will include other adults with knee replacement discussing the challenges they have faced and strategies to overcome barriers to activity.

BEHAVIORAL

Individualized Feedback

Participants will receive individualized feedback from a coach via email. The feedback will specifically focus on participant responses to the 'Apply Your Knowledge' activities and will correspond with the video lessons. Feedback will be weekly during months 1-3 and monthly during months 4-6.

BEHAVIORAL

Online exercise program

MOST Energized! Online Exercise Program

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH
  • University of South Carolina

    lead OTHER

Principal Investigators

  • Christine Pellegrini, PhD · University of South Carolina

  • Jessica Unick, PhD · The Miriam Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-21
Primary Completion
2028-12-30
Completion
2029-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06768762 on ClinicalTrials.gov