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Research Investigating Drug Effects-2 (RiDE-2)

NCT06758596 · Status: NOT_YET_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 144

Last updated 2025-09-19

No results posted yet for this study

Summary

The purpose of this study is to better understand how people's mood, behavior, and brains respond to different recreational drugs. We are also trying to understand why some people may feel differently or their brain may respond differently than other people after taking the same recreational drug.

Conditions

  • Cannabis Use
  • Substance Use Disorder (SUD)
  • Healthy

Interventions

DRUG

Placebo Oral Capsule

A capsule that contains only dextrose filler administered during the first or second laboratory visit.

DRUG

THC

A capsule that contains 7.5 mg of THC as well as dextrose filler administered during the first or second laboratory visit.

Sponsors & Collaborators

  • University of Illinois at Chicago

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-07-15
Primary Completion
2031-03-31
Completion
2031-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06758596 on ClinicalTrials.gov