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Does RPNI Reduce Incidence of Neuroma Formation Following Sural Nerve Biopsy

NCT06754969 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2025-01-01

No results posted yet for this study

Summary

The purpose of our project is to determine if incorporating preventative surgical techniques such as regenerative peripheral nerve interfaces (RPNI) into sural nerve biopsy can reduce the incidence of symptomatic neuroma formation. Findings from this study will inform best practice guidelines and can dramatically impact patient care, improve patient quality of life, and reduce the number of required repeat operations.

Conditions

  • Neuroma of Lower Limb

Interventions

PROCEDURE

Peripheral Nerve Regenerative Interface (RPNI) and Nerve/Muscle Biopsy

RPNI is a surgical technique which wraps denervated muscle targets around severed nerve ends.

PROCEDURE

Biopsy Alone

Sural nerve and muscle biopsy performed in the standard fashion.

Sponsors & Collaborators

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Jenna-Lynn Senger, MD · University of British Columbia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-31
Primary Completion
2026-08-31
Completion
2026-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06754969 on ClinicalTrials.gov