Trial Outcomes & Findings for Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism (NCT NCT06751225)

NCT ID: NCT06751225

Last Updated: 2026-06-04

Results Overview

VAS assessment of overall vision. (0-100 scale; 0=unacceptable 100=excellent)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

40 participants

Primary outcome timeframe

After 3 weeks of lens wear

Results posted on

2026-06-04

Participant Flow

Participant milestones

Participant milestones
Measure
Contact Lens Wear Experience
One week replacement soft contact lenses will be worn for 3 weeks.
Overall Study
STARTED
40
Overall Study
COMPLETED
38
Overall Study
NOT COMPLETED
2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Contact Lens Wear Experience
n=40 Participants
One week replacement soft contact lenses will be worn for 3 weeks.
Age, Categorical
<=18 years
0 Participants
n=9 Participants
Age, Categorical
Between 18 and 65 years
40 Participants
n=9 Participants
Age, Categorical
>=65 years
0 Participants
n=9 Participants
Age, Continuous
27.25 years
STANDARD_DEVIATION 5.90 • n=9 Participants
Sex: Female, Male
Female
27 Participants
n=9 Participants
Sex: Female, Male
Male
13 Participants
n=9 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
6 Participants
n=9 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
34 Participants
n=9 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=9 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=9 Participants
Race (NIH/OMB)
Asian
14 Participants
n=9 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=9 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=9 Participants
Race (NIH/OMB)
White
24 Participants
n=9 Participants
Race (NIH/OMB)
More than one race
1 Participants
n=9 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=9 Participants
Region of Enrollment
United States
40 participants
n=9 Participants

PRIMARY outcome

Timeframe: After 3 weeks of lens wear

VAS assessment of overall vision. (0-100 scale; 0=unacceptable 100=excellent)

Outcome measures

Outcome measures
Measure
Contact Lens Wear Experience
n=38 Participants
One week replacement soft contact lenses will be worn for 3 weeks.
Subjective Assessment of Lens Wear Experience
</= 50
2 Participants
Subjective Assessment of Lens Wear Experience
51-60
0 Participants
Subjective Assessment of Lens Wear Experience
61-70
5 Participants
Subjective Assessment of Lens Wear Experience
71-80
8 Participants
Subjective Assessment of Lens Wear Experience
81-90
11 Participants
Subjective Assessment of Lens Wear Experience
91-100
12 Participants

Adverse Events

Contact Lens Wear Experience

Serious events: 0 serious events
Other events: 3 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Contact Lens Wear Experience
n=40 participants at risk
One week replacement soft contact lenses will be worn for 3 weeks.
General disorders
Cold
7.5%
3/40 • Number of events 3 • Adverse events were collected for each participant's study duration (~1 month).
The Sub-I or PI conducting each study visit asked participants at the beginning of each visit about any changes to health or medications.

Additional Information

Jennifer Fogt

The Ohio State University - Innovation in Eye Care

Phone: 6142928858

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place