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Ephedrine Versus Phenylephrine for Spinal Block - Related Hypotension in Cesarean Delivery

NCT06741410 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 94

Last updated 2025-09-19

No results posted yet for this study

Summary

The study is designed to compare two strategies used in the management of hypotension caused by spinal anesthesia for cesarean section: intravenous phenylephrine given as prophylactic infusion and interventional boluses of intravenous ephedrine. Phenylephrine is currently recommended for battling spinal anesthesia - related sympathectomy, due to some scientific data on possible negative effects of ephedrine on fetal wellbeing. Therefore this study will retrospectively compare both clinical and laboratory data of the newborns delivered by cesarean section where either large dose of ephedrine or continuous infusion of phenylephrine was used for management of hypotension

Conditions

  • Spinal Anesthesia
  • Cesarean Delivery
  • Neonatal Acidosis

Interventions

DRUG

Ephedrine

Intravenous boluses of ephedrine

DRUG

Phenylephrine

Intravenous continuous infusion of phenylephrine

Sponsors & Collaborators

  • Centre of Postgraduate Medical Education

    lead OTHER

Principal Investigators

  • Małgorzata Malec-Milewska, MD, Prof. · Department of Anesthesia and Intensive Care, Orlowski Hospital, Warsaw

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-16
Primary Completion
2025-09-16
Completion
2025-09-16

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06741410 on ClinicalTrials.gov