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Recompensation in Alcohol Related Hepatitis

NCT06740318 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2025-02-27

No results posted yet for this study

Summary

Genetic activity and metabolic changes may be part of the pathogenesis in alcohol related hepatitis. We do not know exactly how alcohol cessation affects liver functions and metabolism.

The aim of this study is to assess the impact of alcohol cessation in patients with alcohol related hepatitis and gain knowledge of the metabolic and genetic functions of the liver during remission and recompensation from alcohol related hepatitis.

The study will assess

1. The effect of alcohol cessation on the liver.
2. The biological mechanisms involved in healing after alvohol-cessation
3. The effect of motivational enhcament therapy in alcohol cessation after alcohol related hepatitis.
4. The metabolic changes of lipids and proteins in the liver Participants are offered motivational enhancement therapy and standard of care.

Conditions

  • Alcoholic Hepatitis (AH)

Interventions

OTHER

Motivational enhancement therapy

The intervention consists of three motivational interviews with the focus to enhance the participants motivation to enter treatment of alcohol use disorder. the interviews are structured and based on the model Motivational enhancement therapy.

Sponsors & Collaborators

  • Copenhagen University Hospital, Hvidovre

    collaborator OTHER

  • The Novo Nordisk Foundation Center for Basic Metabolic Research

    collaborator OTHER

  • Nina Kimer

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-25
Primary Completion
2028-12-31
Completion
2029-12-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06740318 on ClinicalTrials.gov