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Transcranial Doppler (TCD) Ultrasound and Cognition in Cerebral Vascular Disease. (SUNRISE)

NCT06735274 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 517

Last updated 2024-12-16

No results posted yet for this study

Summary

This study aims to contribute to the identification of factors that may be predictive of cognitive function and to provide data on cerebral hemodynamic in ischemic and haemorrhagic stroke. This study will prospectively study cerebral autoregulation, neurovascular coupling and microembolic signs in cerebrovascular patients with ischemic and haemorrhagic stroke and its relationship with cognitive function and functional recovery

Conditions

  • Cerebral Vascular Accident (CVA)/Stroke

Interventions

DIAGNOSTIC_TEST

Cerebral Autoregulation (CAR)

Cerebral Autoregulation (CAR) is the mechanism capable of maintaining cerebral blood flow constant despite fluctuations in blood pressure. The evaluation of dynamic CAR (dCAR) with spontaneous blood pressure variations allows it to be applied in acute and non-collaborating patients

DIAGNOSTIC_TEST

Neurovascular coupling (NVC)

Neurovascular coupling (NVC) is the relationship between neural activity and cerebral blood flow, allowing this activity to be evaluated in spatiotemporal terms .

DIAGNOSTIC_TEST

Microembolic signals (MES)

Microembolic signals (MES)

DIAGNOSTIC_TEST

Montreal Cognitive Assessment (MoCA)

Montreal Cognitive Assessment (MoCA)

DIAGNOSTIC_TEST

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)

DIAGNOSTIC_TEST

Instrumental Activities of Daily Living Scale (IADL)

Instrumental Activities of Daily Living Scale (IADL)

DIAGNOSTIC_TEST

Modified Rankin Scale for Neurologic Disability (mRS)

Modified Rankin Scale for Neurologic Disability (mRS)

Sponsors & Collaborators

  • Hospital de Sao Joao, Porto

    collaborator UNKNOWN

  • RISE Study Group

    collaborator NETWORK

  • Universidade do Porto

    lead OTHER

Principal Investigators

  • Pedro Castro, PhD · Universidade do Porto

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-15
Primary Completion
2023-05-30
Completion
2023-08-30

Countries

  • Portugal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06735274 on ClinicalTrials.gov