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Causal Role of Delta and Theta Oscillations in Hierarchical Cognitive Control

NCT06734377 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2026-03-10

No results posted yet for this study

Summary

The purpose of this clinical trial is to evaluate the effect of rhythmic transcranial magnetic stimulation (TMS) delivered at delta (2.2 Hz) or theta (6.5 Hz) frequency on cognitive control.

This study aims to explore how targeted stimulation at delta and theta frequencies modulates brain activity to enhance cognitive performance in healthy populations.

Conditions

  • Rhythmic Transcranial Magnetic Stimulation (rTMS) Effect on Hierarchical Cognitive Control

Interventions

DEVICE

Delta TMS

TMS will be administered at the frequency of delta oscillation (2.2Hz)

DEVICE

Theta TMS

TMS will be administered at the frequency of theta oscillation (6.5Hz)

DEVICE

Arrhythmic TMS

TMS will be administered arrhythmically. In this intervention, the inter-pulse intervals are randomized between delta and theta durations for each trial, ensuring the same total number of pulses but without rhythmic consistency

Sponsors & Collaborators

  • Florida State University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-20
Primary Completion
2025-10-17
Completion
2025-10-17
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06734377 on ClinicalTrials.gov