Effect of Different Root Canal Sealers on Postoperative Pain

Summary

This randomized clinical study aims to compare postoperative pain in patients after root canal treatments using different root canal filling materials.The root canal pastes that will be tested for postoperative pain in this study have been used worldwide for many years.

Seventy-two patients with single-rooted teeth without pain symptoms but diagnosed with pulpitis and without any previous fillings or prostheses will be randomly divided into three groups according to the root canal sealers. Then the teeth in these groups will be treated with three different root canal sealers. Endodontic treatment will be performed in a single session, following standardized preparation and irrigation protocols, using the warm vertical condensation technique on all teeth.

Patients will be given a Visual Analog Pain Assessment Scale and asked to mark their pain levels between 0 and 10 at 6, 24, 48, 72 hours, and 7 days after root canal treatment. Patients will be called for a check-up at the end of the 7th day, and VAS questionnaires will be collected.

The investigators will be made to determine which root canal sealer causes the least pain.

The null hypothesis of this study was that there would be no difference in post-procedure pain between the groups.

Conditions

• Postoperative Dental Pain
• Root Canal Obturation
• Warm Vertical Compaction
• Root Canal Sealers
• Visual Analog Scale

Interventions

OTHER

Postoperative pain - 6th hour

Patients will be given the VAS Pain Assessment Scale and asked to mark their pain levels between 0 and 10 at 6th hour.

OTHER

Postoperative pain - 24th hour

Patients will be given the VAS Pain Assessment Scale and asked to mark their pain levels between 0 and 10 at 24th hour.

OTHER

Postoperative pain - 48th hour

Patients will be given the VAS Pain Assessment Scale and asked to mark their pain levels between 0 and 10 at 48th hour.

OTHER

Postoperative pain - 72nd hour

Patients will be given the VAS Pain Assessment Scale and asked to mark their pain levels between 0 and 10 at 72nd hour.

OTHER

Postoperative pain - 7 day

Patients will be given the VAS Pain Assessment Scale and asked to mark their pain levels between 0 and 10 at 7 day.

Sponsors & Collaborators

• Dicle University

  lead OTHER

Principal Investigators

• Merve Yeniceri Ozata, Assoc Prof · Dicle University, Faculty of Dentistry, Department of Endodontics

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-01-01

Primary Completion

2025-09-01

Completion

2025-11-01

Countries

• Turkey (Türkiye)

Study Locations