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ClAmpless, Sutureless PartIAl Nephrectomy for Renal Masses

NCT06722807 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 59

Last updated 2026-07-30

No results posted yet for this study

Summary

During partial nephrectomy surgery, efforts at minimizing ischemia while maximizing renal parenchymal volume are desirable to preserve renal function1,2. Not only clamping of the hilum but the renorrhaphy portion of the procedure also can have a significant negative impact on renal function3-5. It is possible to perform this procedure without clamping the hilum and also without formal renorrhaphy. However robust prospective formal evaluation of safety, risks, and potential benefits and whether or not the technique can be employed in a generalized fashion has not been studied.

Demonstration of safety and generalizability may open a whole new avenue of approaching nephron sparing and renal function sparing kidney surgery and decrease potential risks for long term kidney disease in patients with renal masses. This study will investigate the safety, efficacy, and generalizability of the use of clampless, sutureless partial nephrectomy in the treatment of renal cell carcinoma.

Conditions

  • Renal Cell Carcinoma (RCC)

Interventions

PROCEDURE

sutureless, clampless partial nephrectomy

All subjects will undergo a clampless, sutureless robotic partial nephrectomy.

Sponsors & Collaborators

Principal Investigators

  • Paul Crispen, MD · University of Florida

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-10
Primary Completion
2026-08-31
Completion
2027-01-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06722807 on ClinicalTrials.gov