A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China
NCT06718972 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2025-04-27
Summary
This is a retrospective and prospective study planned to include NSCLC patients with Leptomeningeal metastasis (LM) and treated with antitumor therapy after 2018, from multiple centers such as the First Affiliated Hospital of Guangzhou Medical University, Guangdong Sanjiu Brain Hospital, etc., aiming to establish a database related to the treatment strategies of LM patients, and to evaluate the efficacy (eg. Overall Survival/Time to Failure) and safety of different treatment strategies of LM patients, etc., as well as the significance of concomitant testing in LM patients.
Conditions
- Meningeal Metastasis
- Non-Small Cell Lung Cancer
Interventions
- OTHER
-
Not applicable- observational study
This is a retrospective and observational study. Not Applicable
Sponsors & Collaborators
-
Guangzhou Medical University
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-09-01
- Primary Completion
- 2028-12-31
- Completion
- 2028-12-31
Countries
- China
Study Locations
More Related Trials
-
Multimodal Large Model-Driven Risk and Prognosis Assessment for Brain Metastases in Lung Cancer
NCT07107035 ·Status: NOT_YET_RECRUITING
-
An Observational Study to Explore Clinical Characteristics of the Patients With T1 Non-small Cell Lung Cancer
NCT03413956 ·Status: COMPLETED
-
Development and Prospective Validation of a Digital Pathology-based Artificial Intelligence Diagnostic Model for Pan-cancer Lymphatic Metastasis
NCT06517979 ·Status: RECRUITING
-
A Study of Real-world Treatment Patterns and Outcomes in Chinese Advanced NSCLC Patients Who Previously Received at Least 2 Line Treatments
NCT06617390 ·Status: COMPLETED
-
AI-Based Ultrasound Prediction Model for Intracranial Pressure and Prognosis in Lung Cancer Patients With Leptomeningeal Metastasis: A Dual-Center Study
NCT07005791 ·Status: NOT_YET_RECRUITING
-
CTC in Lung Caner Patients With Bone Metastases
NCT04568291 ·Status: UNKNOWN ·Phase: NA
-
Treatment Patterns, Clinical Outcomes, and Healthcare Resource Utilization Associated With Chinese Patients With Advanced Lung Cancer
NCT03505515 ·Status: COMPLETED
-
the Quality of Life Assessment of Lung Cancer Patients in China
NCT01914120 ·Status: UNKNOWN
-
10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma
NCT06366906 ·Status: COMPLETED
-
Prophylactic Cranial Irradiation Versus Observation in Stage IV NSCLC Randomized Controlled Clinical Study
NCT06014450 ·Status: UNKNOWN ·Phase: NA
-
A Real-world Study to Explore Recurrence/Metastases of the NSCLC Patients and the Impact Factors of Patient Survivals
NCT03710616 ·Status: UNKNOWN
-
Efficacy and Safety of Microwave Ablation Combined With Camrelizumab and Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer: a Multicenter, Open, Prospective Study
NCT05532527 ·Status: UNKNOWN ·Phase: NA
-
The Predictive Value of Proteome Profiling for Brain Metastasis in Limited-Stage Small-Cell Lung Cancer
NCT06483919 ·Status: ACTIVE_NOT_RECRUITING
-
Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis
NCT06501391 ·Status: RECRUITING ·Phase: PHASE2
-
Primary Lesion Treatment for Bone Metastases
NCT05665790 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Spinal Metastasis as the First Presentation of Lung Malignancy: Clinical Characteristics and Postoperative Survival
NCT07100444 ·Status: COMPLETED
-
Characteristics, Treatment Patterns and Outcomes for Patients With Surgically Resected Lung Cancers
NCT06255197 ·Status: RECRUITING
-
A Study to Explore Clinical Characteristics and Prognoses of N2 Patients With Non-small Cell Lung Cancer
NCT03429192 ·Status: COMPLETED
-
The Establishment and Clinical Application of a Prediction Model of Lung Cancer Distant Metastasis Based on the Genomic Characteristics of Circulating Tumor Cells
NCT04568720 ·Status: UNKNOWN
-
Risk and Prognosis of Brain Metastasis in Non-Small Cell Lung Cancer
NCT07034365 ·Status: NOT_YET_RECRUITING
-
Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis
NCT04516070 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study on Clinical Features, Treatment Mode and Survival of Bone and Soft Tissue Tumors
NCT05468970 ·Status: RECRUITING
-
Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment
NCT06557967 ·Status: COMPLETED
-
Study on the Accuracy of Proteomics in Evaluating Lymph Node Metastasis Status in Cholangiocarcinoma Patients
NCT05721963 ·Status: UNKNOWN
-
Thoracic Re-irradiation For Locoregionally Recurrent Non-small Cell Lung Cancer
NCT04275687 ·Status: UNKNOWN ·Phase: PHASE2