A Study of IBI363 in Combination With Bevacizumab or Furuitinib in Subjects With Advanced Colorectal Cancer
NCT06717880 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 260
Last updated 2025-02-12
Summary
A Phase 1 study of IBI363 in combination with Bevacizumab or Furuitinib in Subjects with Advanced Colorectal Cancer
Conditions
- Advanced Malignancies
Interventions
- DRUG
-
IBI363 combined with Bevacizumab
IBI363 will be administrated on Day 1 of every 2 weeks or every 3 weeks, intravenous injection. Bevacizumab, intravenous injection.
- DRUG
-
IBI363 + Furuitinib
IBI363 Q2W or Q3W IV,Furuitinib po
Sponsors & Collaborators
-
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- FACTORIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-28
- Primary Completion
- 2025-07-31
- Completion
- 2026-07-31
Countries
- China
Study Locations
More Related Trials
-
Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer
NCT04230187 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Continuing Cetuximab Plus Chemotherapy After First Progression in Wild-type KRAS, NRAS and BRAF V600E Metastatic Colorectal Cancer
NCT04718038 ·Status: COMPLETED
-
SHR-1701 Combined with SHR2554 and BP102 for MCRC
NCT06679673 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab
NCT06540326 ·Status: RECRUITING ·Phase: PHASE2
-
Sintilimab Plus Bevacizumab and Chemotherapy in MSS/pMMR Colorectal With no Liver Metastasis
NCT06973343 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRC
NCT06195670 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Surufatinib With or Wothout Immunotherapy for Advanced Colorectal Cancer in Later Line
NCT05372198 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer
NCT02024607 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC
NCT06168786 ·Status: RECRUITING ·Phase: PHASE2
-
Fruquintinib vs Bevacizumab Combined With Irinotecan Liposome and Capecitabine as Second-Line Therapy for Advanced Metastatic Colorectal Cancer
NCT07051785 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study of SC-0191 in Subjects With Metastatic Colorectal Cancer
NCT06363552 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
XELOX+Bevacizumab and XELIRI + Bevacizumab Alternative Regimen as First-line Treatment for Advanced Colorectal Cancer
NCT03511183 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer
NCT07123441 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Injection of SHR-A1811 Versus Physician Choiced Treatment in Patients With Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-fu, and Irinotecan
NCT06199973 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer
NCT06008119 ·Status: RECRUITING ·Phase: PHASE3
-
A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients.
NCT07283367 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Cetuximab in Combination With Chemotherapy for the Treatment of Metastatic Colorectal Cancer
NCT01564810 ·Status: UNKNOWN ·Phase: PHASE4
-
SBRT Sequential CapeOX Regimen Combined With Bevacizumab and Sintilimab in First-line Treatment of mCRC
NCT05438108 ·Status: UNKNOWN ·Phase: PHASE2
-
An Observational Study of Bevacizumab in Combination With 5-FU-Based Chemotherapy in Chinese Participants With Metastatic Colorectal Cancer
NCT01319877 ·Status: COMPLETED
-
A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC
NCT03303495 ·Status: UNKNOWN ·Phase: PHASE3
-
The Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line Treatment
NCT04984369 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Study of Irinotecan Liposomes in First-line Treatment of Metastatic Colorectal Cancer
NCT06341296 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of FOLFOXIRI Plus Cetuximab vs. FOLFOXIRI Plus Bevacizumab
NCT02515734 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy and Safety of IBI351, Cetuximab β Combined With FOLFIRI as First-line /IBI351, Cetuximab β as Second-line in the Treatment of KRAS G12C-mutated Metastatic Colorectal Cancer
NCT06959589 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Surufatinib Combined With Sintilimab for Advanced MSS-Type Colorectal Cancer : a Phase II Study
NCT04764006 ·Status: UNKNOWN ·Phase: PHASE2