Vericiguat for Heart Failure With Reduced Ejection Fraction After Myocardial Infarction
NCT06717204 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 210
Last updated 2024-12-04
Summary
The effects of vericiguat on cardiac remodeling in patients with chronic stable heart failure after myocardial infarction have not been reported. This project aims to clarify the efficacy and safety of vericiguat in patients with chronic heart failure after myocardial infarction. Patients with chronic stable heart failure with reduced ejection fraction after myocardial infarction in the electronic medical records of Qilu Hospital of Shandong University will be selected and divided into two groups: the treatment group received vericiguat in addition to conventional treatment and the control group received conventional treatment only. After 12-month treatment, the effects of vericiguat on cardiac remodeling and function and cardiovascular adverse events will be evaluated. The results are helpful to provide a new treatment strategy for chronic heart failure after myocardial infarction.
Conditions
- HFrEF - Heart Failure With Reduced Ejection Fraction
- Myocardial Infarction (MI)
Interventions
- DRUG
-
Vericiguat Oral Tablet [Verquvo]
Vericiguat in addition to conventional treatment
- DRUG
-
Prescription Drugs
Conventional treatment only
Sponsors & Collaborators
-
Jinan Central Hospital
collaborator OTHER -
Qianfoshan Hospital
collaborator OTHER -
Qilu Hospital of Shandong University
lead OTHER
Principal Investigators
-
Panpan Hao, MD, PhD · Qilu Hospital of Shandong University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-01-01
- Primary Completion
- 2026-12-31
- Completion
- 2027-12-31
- FDA Drug
- Yes
Countries
- China
Study Locations
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