Efficacy of Organoid-Based Chemotherapy Drug Precision Screening to Guide Treatment for Thyroid Cancer
NCT06713057 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2024-12-03
Summary
The current study aims to explore the potential advantages of chemotherapy that is implemented based on drug sensitivity testing. This pertains to individuals with locally advanced or metastatic poorly differentiated or anaplastic thyroid cancer who have undergone conventional therapy in the past or unresectable patients .
Conditions
- Locally Advanced Thyroid Gland Carcinoma
- Thyroid Cancer
Interventions
- DRUG
-
Cyclophosphamide+Pemetrexed+5-Fluorouracil
IV or PO
- DRUG
-
Cyclophosphamide+Doxorubicin+5-Fluorouracil
IV or PO
- DRUG
-
Vindesine + Cisplatin
IV or PO
- DRUG
-
Doxorubicin + Cisplatin
IV or PO
- DRUG
-
Doxorubicin + Cyclophosphamide + Cisplatin
IV or PO
- DRUG
-
Docetaxel + Doxorubicin
IV or PO
- DRUG
-
Paclitaxel + Carboplatin
IV or PO
- DRUG
-
Paclitaxel + Doxorubicin
IV or PO
- DRUG
-
Paclitaxel + Cisplatin
IV or PO
- DRUG
-
Gemcitabine alone
IV or PO
Sponsors & Collaborators
-
West China Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-12-01
- Primary Completion
- 2025-12-01
- Completion
- 2026-07-01
Countries
- China
Study Locations
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