Trifluridine/tipiracil (TAS-102), Bevacizumab, and Camrelizumab As Third-line or Later-line Therapy of Gastric Cancer
NCT06711471 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 31
Last updated 2024-12-02
Summary
For patients with metastatic gastric cancer, the efficacy of current standard treatments outlined in the guidelines is far from meeting the clinical demand. This study aims to explore the efficacy and safety of trifluridine/tipiracil (TAS-102), bevacizumab plus camrelizumab as a novel third-line or later-line therapy for metastatic gastric cancer patients.
Conditions
- Gastric Cancer Adenocarcinoma Metastatic
Interventions
- DRUG
-
trifluridine/tipiracil (TAS-102), bevacizumab plus camrelizumab
Patients enrolled in this study will receive trifluridine/tipiracil in combination with bevacizumab and camrelizumab, with a treatment cycle of 14 days, until disease progression, death, intolerable toxicity, or other criteria for discontinuation of study treatment as specified in the protocol (whichever occurs first).
Sponsors & Collaborators
-
LIN YANG
lead OTHER
Principal Investigators
-
Lin Yang · Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-11-14
- Primary Completion
- 2026-11-13
- Completion
- 2027-11-13
Countries
- China
Study Locations
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