Expanded Access Program for Patients at Risk for Catheter-related Infections Who Are Not Eligible for DefenCath® Clinical Trials
NCT06707480 · Status: AVAILABLE · Type: EXPANDED_ACCESS
Last updated 2026-05-18
Summary
The EAP for DefenCath is designed to provide access to a broader population of adult and pediatric patients using catheters for various serious medical conditions. A key aspect of this EAP is its focus on individuals who, due to their unique clinical circumstances, are either ineligible for participation in ongoing clinical trials or do not meet the criteria outlined in the current approved FDA label for DefenCath.
Conditions
- Catheter-related Bloodstream Infection
Interventions
- DRUG
-
Taurolidine and Heparin
Catheter Lock Solution
Sponsors & Collaborators
-
CorMedix
lead INDUSTRY
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
More Related Trials
-
Effect of Active Drain Line Clearance on Catheter-Associated Bacteriuria
NCT03816384 ·Status: WITHDRAWN ·Phase: NA
-
Prevention of Dialysis Catheter Malfunction With Prophylactic Use of a Taurolidine Containing Urokinase
NCT02036255 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of a TauroLock™ Based Regimen to 4% Citrate as Lock Solution in Tunneled Haemodialysis Catheters for the Prevention of Bacteraemia and Dysfunction
NCT02789501 ·Status: COMPLETED ·Phase: PHASE4
-
COMPARISON OF KOHLI AND FOLEY CATHETERS IN SUPRAPUBIC CATHETER PATIENTS
NCT03897959 ·Status: UNKNOWN ·Phase: NA
-
Central Line-associated Bloodstream Infection Prevention Using TauroLock-Hep100 in Pediatric Oncology Patients.
NCT05740150 ·Status: UNKNOWN ·Phase: NA
-
Taurolidine Lock in Long Term Parenteral Nutrition
NCT02009189 ·Status: COMPLETED ·Phase: PHASE4
-
Primary Prevention of Infections Related to Chambers Implantable Catheter by a Taurolodine Lock in Patients With Cancer Receiving Parenteral Nutrition
NCT02255318 ·Status: UNKNOWN ·Phase: NA
-
Using the Accuvein Device for Patients Who Are Difficult to Perfuse
NCT06861595 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study of the CAT RX Aspiration Catheter When Used in Patients With Large Occlusive Thrombus in Coronary Arteries
NCT03957473 ·Status: COMPLETED
-
Assessment of Distal Protection Device in Patients at High Risk for Distal Embolism in Acute Coronary Syndrome (ACS)
NCT01460966 ·Status: COMPLETED ·Phase: NA
-
Efficacy Study to Evaluate B-Lock™ as an Antimicrobial Lock Solution in Dialysis Patients With a CVC
NCT01989091 ·Status: TERMINATED ·Phase: PHASE3
-
ATAPAC Study (TauroLock Activity in Adult Cancer Patients)
NCT02279121 ·Status: COMPLETED ·Phase: NA
-
A Post-Market Clinical Follow Up Study to Evaluate BD PureHub™ Disinfecting Cap Use on Needle-Free Connectors
NCT05130762 ·Status: COMPLETED ·Phase: NA
-
Crux Biomedical Vena Cava Filter Study - United States
NCT01120509 ·Status: COMPLETED ·Phase: PHASE3
-
Maintaining Patency in BioFlo Implanted Port Catheters With Saline Only Flushes
NCT02923830 ·Status: TERMINATED ·Phase: PHASE4
-
Clinical Trial Comparing TaurolockTMHep100 (Taurolidine 1.35%) and 0.9% Saline As Prevention of Recurrent Catheter-related Bloodstream Infections
NCT06660641 ·Status: COMPLETED ·Phase: NA
-
Clinical Study Evaluating Use of the CapBuster Medical Device System for the Crossing of Chronic Total Occlusions
NCT04710342 ·Status: UNKNOWN ·Phase: NA
-
Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
NCT01948245 ·Status: UNKNOWN ·Phase: PHASE4
-
Neutrolin Versus Heparin for Locking Hemodialysis Catheters
NCT03425448 ·Status: UNKNOWN ·Phase: NA
-
Evaluating Central Line Hub Contamination Using a Novel Capping Device
NCT01301300 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Antimicrobial Strategy for Device Implantation
NCT07158502 ·Status: NOT_YET_RECRUITING
-
AccuCath™ Intravenous (IV) Device Used by Vascular Access Team (VAT)
NCT01937195 ·Status: COMPLETED ·Phase: NA
-
Endotoxins and Cytokines Removal During Continuous Hemofiltration With oXiris™
NCT03426943 ·Status: COMPLETED ·Phase: NA
-
Addition of Heparin to Taurolock-TM CLS in HD Patients With TCC Dose it Improve Catheter Patency Problems ?
NCT00749619 ·Status: COMPLETED ·Phase: PHASE3
-
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia
NCT00735813 ·Status: COMPLETED ·Phase: PHASE3