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Cardiopulmonary Exercise Testing in Cardiosurgery Patients

NCT06702059 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 130

Last updated 2025-05-15

No results posted yet for this study

Summary

Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications.

Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.

Conditions

  • Postoperative Complications

Interventions

DIAGNOSTIC_TEST

Cardiopulmonary exercise testing

Subjects will undergo pre-operative cardiopulmonary exercise testing.

Sponsors & Collaborators

  • Centre of Cardiovascular and Transplantation Surgery, Czech Republic

    collaborator OTHER

  • St. Anne's University Hospital Brno, Czech Republic

    lead OTHER

Principal Investigators

  • Ivan Cundrle, prof., M.D. · St. Anne's University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2027-12-31
Completion
2028-04-01

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06702059 on ClinicalTrials.gov