A Study of the Effect of Efavirenz on the Plasma Levels of Nemtabrutinib (MK-1026-014)
NCT06698016 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2024-11-20
Summary
The goal of the study is to learn what happens to levels of nemtabrutinib (MK-1026) in a healthy person's body over time. Researchers will compare what happens to nemtabrutinib in the body when it is given with or without another medicine called efavirenz.
Conditions
- Healthy
Interventions
- DRUG
-
Nemtabrutinib
Oral administration
- DRUG
-
Efavirenz
Oral administration
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Medical Director · Merck Sharpe & Dohme LLC
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-07-25
- Primary Completion
- 2023-10-30
- Completion
- 2023-10-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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