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Pharmaco-proteomic Platform to Evaluate Drug Interactions in Liver Transplant Patients

NCT06682325 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2024-11-12

No results posted yet for this study

Summary

The goal of this observational study is to enhance the ability to forecast kidney failure in liver transplant patients in the ICU under multidrug treatment by developing a computer platform that integrates mathematical models of drug interactions, proteomics, and clinical data. The main outcomes it aims to develop are:

1. Design the multidrug web computing platform with available information on drug pair interactions (DDIs).
2. Integrate the proteomic and clinical data of liver transplant patients into the IT platform.
3. Implement the multidrug web platform to predict the clinical evolution of liver transplant patients.

Conditions

  • Drug-drug Interaction
  • Liver Transplantation

Interventions

OTHER

Multi-drug interaction

The clinical impact associated with the use of multiple drugs in liver transplant patients during their stay in ICU will be evaluated.

Sponsors & Collaborators

  • Universidad de Valparaiso

    collaborator OTHER

  • Universidad Adolfo Ibañez

    collaborator UNKNOWN

  • Pontificia Universidad Catolica de Chile

    lead OTHER

Principal Investigators

  • Nelson Barrera, PhD · Pontificia Universidad Catolica de Chile

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-06-01
Primary Completion
2024-12-05
Completion
2025-05-05

Countries

  • Chile

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06682325 on ClinicalTrials.gov