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Characterization of Human Immune Signatures to Zoonotic Virus Exposure in Cambodia

NCT06680843 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2026-05-06

No results posted yet for this study

Summary

This is a biospecimen procurement protocol to characterize the immune response to zoonotic virus exposure in healthy adult humans aged 18 to 65 years with high-risk exposure to animals or their excreta (e.g., guano farming and wet markets), or living within 5 km of animal habitats (e.g., bat caves and bat roosts) in Cambodia.

Conditions

  • Immunity, Humoral

Interventions

PROCEDURE

Whole blood collection

30 mL at Day 0 with optional visits for up to 2 additional whole blood collections at least 30 days apart

Sponsors & Collaborators

  • National Institute of Allergy and Infectious Diseases (NIAID)

    lead NIH

Principal Investigators

  • Christina Yek, MD · NIH/NIAID/Laboratory of Malaria and Vector Research (LMVR)

  • Lon Chanthap, MD · Malaria Vector & Research Laboratory (MVRL) International Center of Excellence in Research Cambodia

  • Ly Sovann, MD, MTCM · Cambodian Center for Communicable Disease (CCDC) Ministry of Health, Cambodia

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-11-01
Primary Completion
2027-10-31
Completion
2028-05-01

Countries

  • Cambodia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06680843 on ClinicalTrials.gov