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Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 3

NCT06669585 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 96

Last updated 2026-05-12

No results posted yet for this study

Summary

This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users. Participants complete the same recognition memory task after self-administering one of two different strains of cannabis flower one day and while not intoxicated another day. Event-related potentials (ERPs) are measured via electroencephalogram (EEG) during the recognition memory task. Blood is collected to quantify THC and CBD exposure. Participants also complete self-report measures of medical history, sleep quality, subjective cognitive function, physical activity, psychological functioning, substance use, and acute drug effects.

Conditions

  • Cannabis
  • Memory
  • Electroencephalography

Interventions

DRUG

Cannabis (smoked flower)

Self-Directed Use (ad-libitum)

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • L. Cinnamon Bidwell

    lead OTHER

Principal Investigators

  • Timothy Curran, PhD · University of Colorado, Boulder

Eligibility

Min Age
21 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-10-09
Primary Completion
2025-12-10
Completion
2025-12-10

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06669585 on ClinicalTrials.gov