ALLG AMLM26 INTERCEPT (Investigating Novel Therapy to Target Early Relapse and Clonal Evolution as Pre-emptive Therapy in AML): A Multi-arm, Precision-based, Recursive, Platform Trial
NCT06664879 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2026-05-15
Summary
To demonstrate the efficacy of targeted and tailored sequential therapy in patients with AML.
Conditions
Interventions
- DRUG
-
MBG-453 + Azacitidine
Given intravenously (by vein)
Sponsors & Collaborators
-
Australasian Leukaemia and Lymphoma Group
collaborator OTHER -
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Courtney DiNardo, MD · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-12-30
- Primary Completion
- 2026-07-31
- Completion
- 2028-07-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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