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Vaginal Microbiome Research Consortium for Africa

NCT06662747 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2025-08-03

No results posted yet for this study

Summary

1. To characterise vaginal microbial community dynamics (bacterial and fungal) from different geographies in Africa to understand the microbial diversity that occurs in women with stable L. crispatus-dominant versus unstable vaginal microbiota.
2. To identify vaginal communities associated with low levels of inflammation in women from different geographies in Africa
3. To examine prevalence and diversity of HPV types circulating in the different geographies and their interaction with the vaginal microbiota
4. To create a biobank of stored samples that can be used in future studies and for the isolation of regionally representative bacterial strains.

Conditions

  • Healthy

Interventions

DIAGNOSTIC_TEST

None - observational study only

No interventions, diagnostics tests for HIV, pregnancy, STIs and BV only

Sponsors & Collaborators

  • Desmond Tutu HIV Foundation

    collaborator OTHER

  • Kenya Medical Research Institute

    collaborator OTHER

  • University of Cape Town

    lead OTHER

Principal Investigators

  • Brian R Kullin, PhD · Research Officer

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-10-15
Primary Completion
2025-12-31
Completion
2026-10-31

Countries

  • Kenya
  • South Africa

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06662747 on ClinicalTrials.gov