Primary and Secondary Drug Resistance Mutations (DRMs) in HIV As a Risk Factor of Failure of ART, Including Two Drugs Based Regimens.
NCT06661317 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2024-10-28
Summary
The presence of drug resistance mutations (DRMs) in HIV plays an important role in ART effectiveness. Despite very good results of ART, there is constant concern about the emergence of HIV strains with DRMs, what may lead to virological suppression failure. The concerns grow especially among patients treated with two drugs based regimens, including long acting therapies in injections (LAI ART) or regimens used in preexposure prophylaxis (PreP).
Conditions
- HIV-1-infection
- DRM
- DRM Gene Mutation
- ART
Interventions
- OTHER
-
no intervention
no intervention
Sponsors & Collaborators
-
Medical University of Warsaw
lead OTHER
Principal Investigators
-
Andrzej Załęski, PhD · Medical University of Warsaw
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-11-01
- Primary Completion
- 2024-11-30
- Completion
- 2024-12-30
Countries
- Poland
Study Locations
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