A Study to Evaluate the Metabolism, Excretion, and Mass Balance of [¹⁴C]Enlicitide Chloride ([¹⁴C]MK-0616) in Healthy Participants (MK-0616-016)
NCT06658626 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2024-10-26
Summary
The purpose of this study is to learn what happens to enlicitide chloride labeled with \[¹⁴C\] in a person's body over time. A label can be added to a study medicine to trace it in a person's body.
Conditions
- Healthy
Interventions
- DRUG
-
[¹⁴C]Enlicitide chloride
IV Injection
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Medical Director · Merck Sharp & Dohme LLC
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-03-10
- Primary Completion
- 2023-08-02
- Completion
- 2023-08-02
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Study to Assess Mass Balance, Pharmacokinetics, Metabolism, and Excretion of Emraclidine in Healthy Adult Male Participants
NCT06301971 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Metabolism and Excretion of BMS-986369 in Healthy Male Participants
NCT05567510 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants
NCT06309394 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Drug Levels, Metabolism, and Removal of BMS-986322 in Healthy Adult Male Participants
NCT06088264 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of MK-8527 in Healthy Adult Participants (MK-8527-013)
NCT06826989 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Drug Levels, Physical and Chemical Changes, and Removal of BMS-986196 in Healthy Male Participants
NCT05981963 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Investigating [14C]-Labeled RO7269162 in Healthy Male Participants
NCT06733298 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Mass Balance of [14C] ABBV-552 in Healthy Male Participants Following Single Oral Dose Administration
NCT06278766 ·Status: COMPLETED ·Phase: PHASE1
-
Mass Balance Study of [14C]-NT-814 Oral Suspension in Healthy Male Subjects
NCT04654897 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study to Investigate the Absorption, Metabolism and Excretion in Healthy Male Subjects
NCT01503866 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Absorption, Metabolism and Excretion of [14C]XZP-3621 in Human
NCT05836805 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]BMS-986419 in Healthy Male Participants
NCT05847439 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Mass Babance and Biotransformation of [14C]SHR6390 in Healthy Adult Male Volunteers
NCT04616742 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Healthy Men to Test How BI 1265162 is Taken up and Processed by the Body
NCT04267276 ·Status: TERMINATED ·Phase: PHASE1
-
Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0980 Following Single Oral Dose Administration in Healthy Postmenopausal Female Subjects
NCT01487239 ·Status: COMPLETED ·Phase: PHASE1
-
Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers
NCT04246749 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB086550
NCT05101369 ·Status: COMPLETED ·Phase: PHASE1
-
A Bioavailability and Pharmacokinetic Study of GDC-0032 in Healthy Volunteers
NCT01967966 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Determine the Absorption, Metabolism, and Excretion of [14C]LX4211 in Healthy Male Subjects
NCT01818232 ·Status: COMPLETED ·Phase: PHASE1
-
Excretion Balance, Pharmacokinetics, and Metabolism Following of [14C]-Venglustat Administration in Healthy Male Subjects
NCT05238714 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-KW-6356
NCT04147910 ·Status: COMPLETED ·Phase: PHASE1
-
Absorption, Metabolism and Excretion of [14C]-Lasmiditan - Single Oral Dose Administration
NCT03040362 ·Status: COMPLETED ·Phase: PHASE1
-
Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers
NCT02264028 ·Status: COMPLETED ·Phase: PHASE1
-
A Pharmacokinetics Study of Radioactive-Labeled GDC-0973 in Healthy Male Volunteers
NCT01711762 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Mass Balance of [14C] ABBV-903 in Healthy Male Participants Following Single Oral Dose Administration
NCT05995366 ·Status: COMPLETED ·Phase: PHASE1