A Clinical Study of MK-1708 in Healthy Elderly Participants (MK-1708-005)
NCT06647628 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2025-05-15
Summary
The purpose of this study is to learn about the safety of MK-1708, and how well elderly people tolerate it. The study will also measure what happens to MK-1708 in a healthy elderly person's body over time (pharmacokinetic or PK study). Researchers will learn if at least 1 dose level of MK-1708 will be safe, well-tolerated, and will be above a certain level in people's blood after 24 hours.
Conditions
- Healthy
Interventions
- DRUG
-
MK-1708
MK-1708 oral suspension
- DRUG
-
Placebo oral suspension
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Study Director · Merck Sharp & Dohme LLC
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- TRIPLE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 65 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-11-04
- Primary Completion
- 2025-03-31
- Completion
- 2025-03-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Safety, Tolerability and Pharmacokinetics of AM1476 in Healthy Subjects
NCT04691115 ·Status: COMPLETED ·Phase: PHASE1
-
A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of MK-1064 (MK-1064-001)
NCT02549014 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone Bromide
NCT01366365 ·Status: COMPLETED ·Phase: PHASE1
-
MT1013 Clinical TRIAL In Healthy Subject
NCT04783090 ·Status: COMPLETED ·Phase: PHASE1
-
Study of NAV-240 in Healthy Volunteers
NCT06181786 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SR1375
NCT05026008 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2082 in Healthy Male Subjects
NCT03402178 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability and Pharmacokinetics of PAC-14028 Cream in Healthy Male Subjects
NCT02309008 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability and Pharmacokinetics Study of MK-7252 in Healthy Adult Participants (MK-7252-001)
NCT03326986 ·Status: COMPLETED ·Phase: PHASE1
-
A First-in-Human Single and Multiple Ascending Dose Study of MT-201
NCT07219368 ·Status: RECRUITING ·Phase: PHASE1
-
Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects
NCT05158335 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Escalating Single Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of ND-L02-s0201 Injection in Normal Healthy Subjects
NCT01858935 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of SHR -2001 in Healthy Subjects
NCT05942612 ·Status: COMPLETED ·Phase: PHASE1
-
Single-Ascending Dose Study of MK-2060 in Healthy Chinese Male Adult Participants (MK-2060-009)
NCT06843993 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study of ADX-626 in Healthy Participants
NCT07081503 ·Status: RECRUITING ·Phase: PHASE1
-
To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects
NCT01818869 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetic/Pharmacodynamic Characteristics of KMRC011
NCT03585803 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Conducted in Healthy Male Subjects to Investigate the Safety and Tolerability of AC-76, Its Fate in the Body, and Its Effect on the Body
NCT03173625 ·Status: COMPLETED ·Phase: PHASE1
-
A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants
NCT05662215 ·Status: TERMINATED ·Phase: PHASE1
-
A Single Dose Study Of The Safety And Investigational Product Level Measurement In Healthy Subjects
NCT01284036 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety, Tolerability, Pharmacokinetics, and Immunogenicity Study of CNTO 6785 in Healthy Volunteers
NCT01288196 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ID110521156 in Healthy Adult Subjects
NCT06635226 ·Status: RECRUITING ·Phase: PHASE1
-
Single and Multiple Ascending Dose Pharmacokinetic Study of TR701 in Healthy Adults
NCT00671814 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability and Pharmacokinetics Study Assessing Ascending Single Oral JTK-853 Doses in Healthy Subjects
NCT01475981 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability of SOBI002 in Healthy Volunteers Following Single and Repeated Administration
NCT02083666 ·Status: TERMINATED ·Phase: PHASE1