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Pilot fMRI Studies of Aging-Related Effects of THC

NCT06647524 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2025-10-09

No results posted yet for this study

Summary

The purpose of this study is to begin investigating acute impairment of various forms of memory and learning by Tetrahydrocannabinol (THC) in cannabis (CNB) compared to placebo, in a 2-session per subject double-blind, random assignment, placebo-controlled counterbalanced design in young to middle-aged adults.

Conditions

  • THC

Interventions

DRUG

THC

Participants will be administered 0.5g of vaporized THC cannabis (12% THC cannabis)

DRUG

Placebo

Participants will be administered identical plant material from which all THC has been removed by solvent extraction.

Sponsors & Collaborators

  • Biopharmaceutical Research Company

    collaborator UNKNOWN

  • Bloom Labs Cannabis Solutions

    collaborator UNKNOWN

  • Yale University

    lead OTHER

Principal Investigators

  • Godfrey Pearlson, M.D · Founding Director, Olin Neuropsychiatry Center; Yale University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-01
Primary Completion
2027-12-31
Completion
2027-12-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06647524 on ClinicalTrials.gov