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Effect of Targeted Endodontic Microsurgery on Quality of Life and Healing on Mandibular Molars

NCT06643676 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2026-05-08

No results posted yet for this study

Summary

Targeted endodontic microsurgery represents precise and advanced approach to resolving persisting chronic periapical periodontitis after non- surgical root canal treatment. This specialised procedure involves accessing the root tip of the tooth under high magnification using dental operating microscopes and employing microsurgical instruments to remove infected or inflamed tissue, as well as any pathological lesions present in the periapical region. Targeted Endodontic Microsurgery is useful for osteotomy and root- end resection when exacting control of depth, diameter, and angulation of osteotomy and root end resection is necessary. Using a CBCT(cone beam computed tomography) designed 3D - printed surgical guideis a more accurate method for access to the apical portion of the root during surgical endodontics compared with a "freehand" CBCT - approximated conventional method. These guided have the potential to increase accuracy and precision and to reduce intraoperative time as well as postoperative complications. Additionally, it provides a viable treatment option for patients who may not be candidates for traditional root canal therapy or retreatment due to anatomical complexities or previous treatment failures.

Conditions

  • Periapical Diseases
  • Periapical Periodontitis
  • Periapical Cyst
  • Periapical Granuloma
  • Periapical Pathology
  • Endodontic Microsurgery
  • Targeted Endodontic Microsurgery

Interventions

PROCEDURE

Targeted Endodontic Microsurgery Using 3d Printed surgical guide using the patient's CBCT data

Patients with apical periodontitis with intact cortex in madibular molars receiving Targeted Endodontic surgery or Guided Endodontic Microsurgery with surgical guide fabricated using the cbct data following failure of non surgical root canal treatment

PROCEDURE

Conventional Endodontic Microsurgery with a free hand procedure using bur and CBCT analysis

A conventional endodontic microsurgery using arbitrary localisation technique using the cbct data and performing the surgery with a carbide bur.

Sponsors & Collaborators

  • Postgraduate Institute of Dental Sciences Rohtak

    lead OTHER

Principal Investigators

  • Jigyasa grover, MDS · PGIDS ROHTAK, HARYANA

  • sanjay Tewari, MDS · PGIDS ROHTAK HARYANA

  • MOHAMMED MUZAFFAR KHAN, BDS · PGIDS ROHTAK HARYANA

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-07-01
Primary Completion
2025-12-15
Completion
2025-12-31

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06643676 on ClinicalTrials.gov