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Impact Of Kidney Failure On The Regulation Of Humoral Response To Vaccination

NCT06635525 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 146

Last updated 2026-03-30

No results posted yet for this study

Summary

The aim of this observational study is to determine if and how kidney failure affects the development of protective immune responses following vaccination in patients on chronic dialysis.

Researchers will compare the effectiveness of the influenza vaccine in inducing protective antibodies between hemodialysis patients and subjects without chronic kidney disease.

Participants will:

* Be enrolled at the time of influenza vaccination
* Visit the clinic at 7, 14, 30, 60, and 120 days after vaccination
* Be asked to provide relevant clinical information and a blood sample at each visit

Conditions

  • Chronic Kidney Disease Requiring Chronic Dialysis
  • Vaccine Response

Interventions

BIOLOGICAL

Influenza vaccination

Single-dose

BIOLOGICAL

SARS-CoV-2 vaccine

Single-dose

Sponsors & Collaborators

  • Fondazione Cariplo

    collaborator UNKNOWN

  • Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-10-16
Primary Completion
2026-07-31
Completion
2026-07-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06635525 on ClinicalTrials.gov