MedTrace Logo

Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA

NCT06611618 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-02-27

No results posted yet for this study

Summary

The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is:

● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population?

Participants will undergo:

* Muscle force assessment on a dynamometer
* Muscle power assessment on a dynamometer and on isntrumented stairs
* Home-based mobility monitoring
* Full lower limb MRI acquisition
* Gait assessment

Conditions

  • Knee Osteoarthritis (Knee OA)
  • Falls Prevention

Interventions

OTHER

Muscle force assessment

Isometric dynamometry (Maximal Voluntary Isometric Contraction)

OTHER

Home-based mobility monitoring

Mobility monitoring with wearable sensors

DIAGNOSTIC_TEST

Magnetic Resonance Imaging

Full lower limb MRI

OTHER

Muscle power assessment

Isokinetic dynamometry test Stair ascent/descent on instrumented stairs

OTHER

Gait assessment

Motion capture, surface EMG and gorund reaction force data

Sponsors & Collaborators

  • Istituto Ortopedico Rizzoli

    lead OTHER

Principal Investigators

  • Lisa Berti, Professor · IRCCS Istituto Ortopedico Rizzoli

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
65 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-30
Primary Completion
2026-06-30
Completion
2026-12-12

Countries

  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06611618 on ClinicalTrials.gov