Postoperative Adjuvant Therapy for Stage II-III Gastric Cancer
NCT06609759 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 197
Last updated 2026-05-05
Summary
For patients with stage II-III gastric cancer after radical D2 resection and R0 resection, postoperative adjuvant therapy guided by ctDNA-MRD (MRD-GATE external cohort) was not inferior to the standard chemotherapy regimen (this cohort).
Conditions
- Stage II-III Gastric Cancer
Interventions
- DRUG
-
Standard chemotherapy regimen
In terms of postoperative adjuvant treatment, treatment is based on the guideline standard treatment plan, which can be adjusted according to the doctor's experience.
Sponsors & Collaborators
-
Shandong Provincial Hospital
collaborator OTHER_GOV -
Jinan Central Hospital
collaborator OTHER -
Yantai Yuhuangding Hospital
collaborator OTHER -
The Affiliated Hospital of Qingdao University
collaborator OTHER -
Qilu Hospital of Shandong University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-01-01
- Primary Completion
- 2028-01-01
- Completion
- 2029-01-01
Countries
- China
Study Locations
More Related Trials
-
Compare S-1 for 6 Months to 1 Year as Adjuvant Chemotherapy After D2 Resection in Patients With Gastric Cancer Staged II , IIIA or IIIB.
NCT02736552 ·Status: WITHDRAWN ·Phase: PHASE3
-
Adjuvant Serplulimab and Trastuzuma and Chemotherapy in Her-2+ Gastric Cancer
NCT05975749 ·Status: RECRUITING ·Phase: PHASE2
-
Intraperitoneal Chemotherapy Guided by the Detection of DNA in Peritoneal Lavage Fluid in Patients With Gastric Cancer
NCT05497739 ·Status: UNKNOWN ·Phase: PHASE2
-
T- XELOX in HER2-positive Stage III Gastric Cancer After D2 Gastrectomy
NCT02250209 ·Status: UNKNOWN ·Phase: PHASE2
-
Effect of Adjuvant Chemotherapy Cycles on Patients With Node-negative Gastric Cancer Following Neoadjuvant Chemotherapy
NCT06277453 ·Status: ACTIVE_NOT_RECRUITING
-
The Effect of Traditional Chinese Treatment Combined Adjuvant Chemotherapy in IIIb and IIIc Gastric Cancer
NCT03607656 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study of Raltitrexed Plus Docetaxel Versus Docetaxel as Second-line Chemotherapy in Subjects With Gastric Cancer
NCT01836120 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase III Study OF the Gastric Surgery on Advanced Stage Gastric Cancer
NCT00260884 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase II Study of Total Neoadjuvant Therapy for Locally Advanced Gastric Cancer
NCT04062058 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Confirm the Accuracy of Locally Advanced Gastric Cancer Diagnosis
NCT04440605 ·Status: UNKNOWN
-
The Safety and Efficacy of PD-1 Monoantrapical Chemotherapy in the Treatment of Local Advanced Stomach Cancer
NCT05000554 ·Status: RECRUITING ·Phase: PHASE2
-
Three Drugs in Advanced Gastric Cancer Neoadjuvant Chemotherapy for Stage Ⅲ Clinical Study
NCT02555358 ·Status: COMPLETED ·Phase: PHASE2
-
Feasibility of Circulating Tumor DNA Based Minimal Residual Disease-Guided Adjuvant Therapy in Locally Advanced Gastric Cancer With Neoadjuvant Treatment: An Adaptive Trial (MRD-ATLAS)
NCT07257380 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
First-Line and Neoadjuvant Immunotherapy for Gastric Cancer
NCT06727981 ·Status: RECRUITING
-
the Optimal Surveillance Frequency for Stage II/III Gastric Cancer
NCT05465993 ·Status: COMPLETED
-
Preoperative Stomach Cancer Induction Chemotherapy and Radiation Therapy
NCT03223740 ·Status: UNKNOWN ·Phase: PHASE3
-
Trastuzumab Plus Docetaxel and Capecitabine For First Line Treatment of Her2-Positive Advanced Gastric Cancer
NCT02004769 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial of Two Adjuvant Chemotherapy Regimens for Postoperative Gastric Cancer
NCT04351867 ·Status: UNKNOWN ·Phase: PHASE3
-
Function Preserving Gastrectomy for T1/2 Gastric Cancer Patients
NCT03874871 ·Status: UNKNOWN
-
Duration of Adjuvant Chemotherapy for Gastric Cancer Patients at Pathological N3 Stage
NCT06194981 ·Status: RECRUITING
-
Receiving Modified Chemotherapy Followed With Radical Resection After Neoadjuvant Chemotherapy
NCT03322969 ·Status: UNKNOWN ·Phase: PHASE2
-
Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China
NCT06846996 ·Status: RECRUITING
-
A Comparison of Laparoscopic With Open Distal Gastrectomy in Advanced Gastric Cancer After Neoadjuvant Chemotherapy
NCT02404753 ·Status: UNKNOWN ·Phase: PHASE2
-
Predictive Biomarkers in Stage II/III Gastric Cancer for Adjuvant Chemotherapy
NCT01905969 ·Status: UNKNOWN
-
Neoadjuvant Chemotherapy for Patients With Advanced Gastric Cancer in ERAS Programs for Radical Gastrectomy
NCT03238404 ·Status: COMPLETED ·Phase: NA