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Preoperative Chest CT-imaging in Surgical Aortic Valve Replacement with or Without CABG

NCT06603454 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 380

Last updated 2024-09-19

No results posted yet for this study

Summary

Rationale When determining the strategy for aortic valve replacement, echocardiography is still considered the golden standard (1). While pre-procedural MSCT is standard of care in TAVR patients, this is not yet part of routine clinical practice in SAVR patients. The researchers hypothesise that when atherosclerosis of the ascending aorta is identified preoperatively on contrast-enhanced multi-slice computed tomography (MSCT), the subclinical perioperative stroke rate (as detected on diffusion-weighted magnetic resonance imaging (DW-MRI)) can be reduced by modification of the operative strategy if necessary.

Conditions

  • Aortic Valve Stenosis

Interventions

RADIATION

Preoperative CT

Preoperative contrast enhanced CT

Sponsors & Collaborators

  • ZonMw: The Netherlands Organisation for Health Research and Development

    collaborator OTHER

  • Romy Hegeman

    lead OTHER

Principal Investigators

  • Patrick Klein, MD, PhD · St. Antonius Hospital

  • Prof. Jurriën C ten Berg, MD, PhD · St. Antonius Hospital

  • Martin C Swaans, MD, PhD · St. Antonius Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-12-04
Primary Completion
2025-04-01
Completion
2025-12-01

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06603454 on ClinicalTrials.gov