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Differential Assessment of Hypertonia

NCT06596187 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2024-10-15

No results posted yet for this study

Summary

Spasticity and rigidity are common symptoms of central nervous system injuries, such as spinal cord injury and Parkinson's disease, and result in distinct patterns of increased resistance during passive joint movements. Spasticity is characterized by a velocity-dependent increase in stretch reflexes, accompanied by exaggerated tendon responses, while rigidity is marked by consistent resistance throughout the range of motion, traditionally considered independent of stretch velocity. However, recent studies suggest that rigidity may also be influenced by stretch velocity. This study aims to investigate muscle tone by examining spasticity, rigidity, and normal muscle function through neural and biomechanical changes. Standard clinical tools, such as the Modified Ashworth Scale and Unified Parkinson's Disease Rating Scale, along with additional assessments like the Myoton and Post-Activation Depression (PAD), will be employed.

Conditions

  • SCI - Spinal Cord Injury
  • PD - Parkinson's Disease

Interventions

PROCEDURE

Continuous passive motion device (CPM) of ankle - fast

Continuous passive motion device (CPM) of ankle at 1HZ(60rpm) for 10 repetitions

PROCEDURE

Continuous passive motion device (CPM) of ankle - slow

Continuous passive motion device (CPM) of ankle 0.25HZ (15rpm) for 10 repetitions

Sponsors & Collaborators

  • Chang Gung University

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-10-09
Primary Completion
2026-08-31
Completion
2026-08-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06596187 on ClinicalTrials.gov