A Phase 2 Study to Evaluate JCXH-105, an srRNA-based Herpes Zoster Vaccine
NCT06581575 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 467
Last updated 2026-04-23
Summary
The goal of this clinical trial is to assess the safety and immunogenicity of an srRNA-based vaccine, JCXH-105, in the prevention of Herpes Zoster (Shingles).
Subjects will be randomized to receive either JCXH-105 or Shingrix.
Conditions
- Shingles
- Herpes Zoster (HZ)
- Infectious Diseases
Interventions
- BIOLOGICAL
-
JCXH-105
IM injection
- BIOLOGICAL
-
Shingrix
IM injection
Sponsors & Collaborators
-
Tigermed Consulting Co., Ltd
collaborator INDUSTRY -
Immorna Biotherapeutics, Inc.
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-10-16
- Primary Completion
- 2026-08-31
- Completion
- 2026-08-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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