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Local Methotrexate Injections for the Treatment of Nail Psoriasis

NCT06578728 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 1

Last updated 2026-03-25

No results posted yet for this study

Summary

The investigators hope to learn the efficacy of methotrexate injections for treatment of nail psoriasis.

Conditions

  • Nail Psoriasis

Interventions

DRUG

Methotrexate

25mg/mL intralesional injection into nail bed/nail matrix

DRUG

Triamcinolone Acetonide 10mg/mL

10mg/mL intralesional injection into nail bed/nail matrix

DRUG

Saline

saline intralesional injection into nail bed/nail matrix

Sponsors & Collaborators

  • Weill Medical College of Cornell University

    lead OTHER

Principal Investigators

  • Shari Lipner, MD, PhD · Weill Medical College of Cornell University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-10
Primary Completion
2026-06-30
Completion
2026-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06578728 on ClinicalTrials.gov