Thailand HIV and Stigma Reduction Study

Summary

This project will develop a multi-component, technology-delivered intervention designed to reduce HIV and intersectional stigma and improve the use of HIV pre-exposure prophylaxis (PrEP) among HIV-negative Thai vulnerable emerging adults (18-29 years).

Conditions

• Pre-Exposure Prophylaxis

Interventions

BEHAVIORAL

Mobile Healthy Choices (mHC)

mHC is a four-session, 20-minute, motivational interviewing-based intervention, which will be delivered on the CIAS platform. It will be tailored to participants' responses given during the interaction in the intervention. In the first two sessions, the (virtual) counselor will motivate participants to overcome stigma and utilize HIV prevention services by using tailored motivational interviewing strategies, develop an individualized change goal based on their readiness, and provide cognitive behavioral strategies. In the last two sessions, the counselor will review the change plan, monitor progress, and provide support for sustained behavioral change. The sessions will occur within three months after baseline.

BEHAVIORAL

Finding Respect and Ending Stigma around HIV (FRESH)

FRESH content includes six 10-15 minute sessions with interactive, culturally sensitive multimedia modules, which will be delivered on the CIAS platform. The content will aim to improve self-efficacy, reduce intersectional stigmas and promote HIV preventative behaviors. The sessions will occur within three months after baseline.

BEHAVIORAL

Standard PrEP Counseling

All participants will receive one-on-one, face to face counseling from focusing on sexual and behavioral risk assessment for HIV/STIs, risk reduction, and HIV prevention. For those not on PrEP, the sessions will focus on risk perception, awareness of PrEP, and facilitators and barriers to PrEP access. For those on PrEP, the sessions will focus on adherence. The counseling will be provided at baseline, 3 months, and 6 months.

Sponsors & Collaborators

• National Institute of Mental Health (NIMH)

  collaborator NIH

• Institute of HIV Research and Innovation Foundation, Thailand

  collaborator OTHER

• University of Massachusetts, Worcester

  lead OTHER

Principal Investigators

• Bo Wang, PhD · University of Massachusetts, Worcester

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Max Age

29 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2025-02-20

Primary Completion

2026-12-31

Completion

2027-08-14

Countries

• Thailand

Study Locations