Study on Neuropsychiatric Behavior in Cadmium-exposed People
NCT06572566 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 160
Last updated 2026-04-21
Summary
This study hypothesized that excessive cadmium is related to clinical pain, depression, and cognitive impairment, and that related indicators will improve after cadmium is eliminated.
Conditions
- Cadmium Exceeds the Standard
Interventions
- OTHER
-
Non-invasive examination and assessment.
1\) Test the blood and urine components of all subjects to evaluate the damage to kidney function caused by excessive cadmium. 2) Conduct MRI examinations on all subjects to evaluate changes in brain functional connectivity, metabolism, and structure after excessive cadmium exposure. 3) Conduct bone density examinations on all subjects to evaluate changes in bone density after excessive cadmium exposure. (3) Clinical psychiatric assessment: All subjects will be assessed on their mental and psychological conditions such as pain, cognitive function, depression, anxiety, mania, sleep quality, and suicide risk.
Sponsors & Collaborators
-
Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Fang Pei · Hunan Occupational Disease Prevention and Control Institute
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-01-08
- Primary Completion
- 2026-03-30
- Completion
- 2026-03-30
Countries
- China
Study Locations
More Related Trials
-
The Efficacy and Cerebral Mechanism of Intradermal Acupuncture for Major Depressive Disorder
NCT05720637 ·Status: COMPLETED ·Phase: NA
-
Effect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking Study
NCT04071886 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Anyu Peibo With Placebo in Treatment of MDD in China
NCT04210973 ·Status: UNKNOWN ·Phase: PHASE3
-
A One-year Trajectory of Depression Status Changes in Older Adults With MCI and SD: a Longitudinal Cohort Study
NCT06308627 ·Status: COMPLETED
-
Objective Diagnostic Markers and Personalized Intervention in MDD Patients
NCT02023567 ·Status: UNKNOWN ·Phase: NA
-
Serotonin Transporter Density in Late-life Depression With and Without Dementia
NCT01548937 ·Status: COMPLETED ·Phase: PHASE2
-
Psychopharmacotherapy for Depressive Patients
NCT06054321 ·Status: RECRUITING ·Phase: NA
-
Multi-factor Model Constraction for Early Warning and Diagnosis of MDD
NCT05529576 ·Status: UNKNOWN ·Phase: PHASE4
-
Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to Clinical Practice
NCT07009223 ·Status: RECRUITING ·Phase: NA
-
Construction of Nutritional Path for Mental Diseases
NCT04504058 ·Status: UNKNOWN
-
Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study
NCT07203144 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Exploring Blood Plasma Metabolomics: Unraveling the Metabolic Landscape in Treatment-Resistant Adolescent Depression
NCT06331572 ·Status: COMPLETED
-
Enhancing Processing Speed and Executive Functioning in Depressed Older Adults With Computerized Cognitive Training
NCT04836533 ·Status: WITHDRAWN ·Phase: PHASE1
-
Treatment Response Biomarkers in MDD
NCT05585047 ·Status: RECRUITING
-
A Single-center Randomized Controlled Study on the Effect of Pharmacogenomics Trial on Clinical Efficacy in Patients With Depression
NCT05959187 ·Status: COMPLETED ·Phase: NA
-
A Study of Xiongdan Wan Treating Depression
NCT05136365 ·Status: COMPLETED ·Phase: PHASE2
-
Predictive Effect of Neuroinflammatory Factors of the MECT in Treatment of Senile Depression
NCT05597566 ·Status: UNKNOWN
-
Effect of Probiotic on Comorbidity of Depression and Constipation
NCT04570072 ·Status: UNKNOWN ·Phase: NA
-
Establish a Specific Cohort Database for Depressive Disorders
NCT05095662 ·Status: ACTIVE_NOT_RECRUITING
-
A Clinical Study of Trazodone Hydrochloride Prolonged-Release Tablets for Treatment of Depression
NCT01524497 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Pharmacotherapy and Psychotherapy for MDD After Remission on Psychology and Neuroimaging
NCT01831440 ·Status: UNKNOWN ·Phase: NA
-
Impact of Immune Challenge on Triple Network Connectivity in Humans
NCT02653235 ·Status: UNKNOWN ·Phase: NA
-
Investigation on Risk Factors for Suicide Among Chinese Patients With Mood Disorders
NCT07281729 ·Status: ENROLLING_BY_INVITATION
-
Prevalence of Depression and Anxiety in Patients Seeking Medical Care at General Health Care Settings in China
NCT00478829 ·Status: COMPLETED
-
Efficacy and Safety of Intradermal Acupuncture for Major Depressive Disorder
NCT05605002 ·Status: RECRUITING ·Phase: NA