Perioperative Risk of Immunotherapy Based Neoadjuvant and Conversion Therapy for Hepatocellular Carcinoma
NCT06571396 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2024-08-26
Summary
This study aims to retrospectively collect a cohort of participants with hepatocellular carcinoma who received immunotherapy-based neoadjuvant/translational treatment. A multi-dimensional and multi-method analysis plan will be adopted. The goal is to provide solutions for better application of neoadjuvant immunotherapy and to offer better evidence for conducting prospective clinical research on hepatocellular carcinoma.
Conditions
- Carcinoma, Hepatocellular
- Immunotherapy
Sponsors & Collaborators
-
Qilu Hospital of Shandong University
lead OTHER
Principal Investigators
-
Tao Li · Shandong University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-04-01
- Primary Completion
- 2025-08-01
- Completion
- 2026-08-03
Countries
- China
Study Locations
More Related Trials
-
ICIs With and Without MWA in Advanced Hepatocellular Carcinoma
NCT06581497 ·Status: COMPLETED
-
Study on the Efficacy and Safety of Conversion Therapy in Patients With Initially Unresectable Hepatocellular Carcinoma
NCT06365034 ·Status: RECRUITING
-
Study on the Classification of Comprehensive Treatment Effect of Hepatocellular Carcinoma
NCT06542796 ·Status: RECRUITING ·Phase: NA
-
Pre-operative Neoadjuvant Therapy Combined With Surgery for Treating Stage III Hepatocellular Carcinoma
NCT04961138 ·Status: UNKNOWN ·Phase: NA
-
Real-world Study for Patients With Advanced Hepatobiliary Tumors
NCT03892577 ·Status: RECRUITING
-
Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeted Drugs / Locoregional Therapy in the Treatment of Hepatocellular Carcinoma
NCT05609695 ·Status: UNKNOWN
-
A Prospective Observational Cohort Study on Dynamic CD8+ T-cell Profiling and Multi-omics Biomarkers for Predicting Conversion Therapy Response in Unresectable Hepatocellular Carcinoma
NCT07117279 ·Status: NOT_YET_RECRUITING
-
Safety and Efficacy of Autoimmune Cell Therapy for Patients With Hepatocellular Carcinoma
NCT05105815 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Therapeutic Effects of Immuno-targeted Therapy Combined With or Without RT for HCC
NCT06639971 ·Status: NOT_YET_RECRUITING
-
Radical Surgery Followed by Immunotherapy Using Precision T Cells Specific to Multiple Common Tumor-Associated Antigen for the Treatment of Hepatocellular Carcinoma
NCT02632188 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Effects of Antiviral Therapy on Patients With HBV-related HCC
NCT05406089 ·Status: COMPLETED
-
A Retrospective Study on the Treatment of Intermediate and Advanced Liver Cancer.
NCT06205732 ·Status: RECRUITING
-
Combination Therapy of Microwave Ablation and Cellular Immunotherapy for Hepatocellular Carcinoma
NCT02851784 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Open Label Trial of Immunotherapy for Advanced Liver Cancer
NCT02256514 ·Status: UNKNOWN ·Phase: PHASE2
-
Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of Recurrence
NCT06954116 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Nivolumab Plus Ipilimumab as Neoadjuvant Therapy for Hepatocellular Carcinoma (HCC)
NCT03510871 ·Status: COMPLETED ·Phase: PHASE2
-
The Prediction Biomarkers of Survival Outcome for Severe Immune-related Hepatitis
NCT05326906 ·Status: COMPLETED
-
Neoadjuvant Intra-tumor Double Immunotherapy for Hepatocellular Carcinoma.
NCT06492408 ·Status: RECRUITING ·Phase: PHASE2
-
By Using Adoptive Transfer of Autologous NK Cells to Prevent Recurrence of Hepatocellular Carcinoma After Curative Therapy
NCT02725996 ·Status: UNKNOWN ·Phase: PHASE2
-
Analysis of Expression of Specific Markers and Their Prognostic Significance in Hepatocellular Carcinoma
NCT00911196 ·Status: COMPLETED
-
Efficacy and Safety of Transarterial Therapies+Donafenib + Anti-PD-1 Antibody for uHCC: A Retrospective Real-world Study
NCT05638438 ·Status: UNKNOWN
-
Camrelizumab Combined With Apatinib Mesylate and TACE in the Perioperative Treatment of Hepatocellular Carcinoma
NCT05613478 ·Status: RECRUITING ·Phase: PHASE3
-
Non-inferiority Study of Unresectable Hepatocelluar Carcinoma Receiving Stereotactic Radiotherapy Combined With Hepatic Arterial Chemoembolization Compared With Conversion Hepatectomy
NCT05057104 ·Status: UNKNOWN
-
The Efficacy and Safety of EOB-MRI Guided Microwave Ablation for Early HCC: A Multicenter, Prospective, Observational Study
NCT06096896 ·Status: ACTIVE_NOT_RECRUITING
-
Prognostic Impact of Adjuvant Therapy in Primary Hepatic Sarcomatoid Carcinoma
NCT06950814 ·Status: RECRUITING