Evaluation of Reflex Tear Production
NCT06565624 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2025-01-23
Summary
The purpose of this study is to evaluate reflex tear production following cotton swab nasal stimulation in subjects with dry eye disease (DED).
Conditions
Interventions
- PROCEDURE
-
Cotton Swab Nasal Stimulation
Nostril probing for the purpose of producing reflex tearing
Sponsors & Collaborators
-
Alcon Research
lead INDUSTRY
Principal Investigators
-
Clinical Trial Lead, Pharma · Alcon Research, LLC
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-10-17
- Primary Completion
- 2024-11-07
- Completion
- 2024-11-07
Countries
- United States
Study Locations
More Related Trials
-
Effects of NOV03 on the Tear Film
NCT05723770 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Investigate the Effect of 0.003% AR-15512 on Subjects With Dry Eye Disease
NCT06544694 ·Status: COMPLETED ·Phase: PHASE3
-
Diurnal Variation in Tear Osmolarity
NCT01321424 ·Status: COMPLETED
-
Efficacy and Safety Study of FID 119515A
NCT01833117 ·Status: COMPLETED ·Phase: NA
-
Biochemical Factors for a Dry Eyed Population
NCT00522847 ·Status: COMPLETED
-
Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests
NCT04125134 ·Status: TERMINATED ·Phase: PHASE4
-
Diagnostic Evaluation of the Tear Film
NCT00761917 ·Status: COMPLETED
-
A Study of AL-38583 Ophthalmic Solution 0.05%, 0.010% Versus AL-38583 Vehicle for Dry Eye
NCT00893139 ·Status: COMPLETED ·Phase: PHASE2
-
Tear Production by Nasal Neurostimulation Compared to Active Control
NCT02970799 ·Status: COMPLETED ·Phase: NA
-
Assessment of Inflammatory and Functional Changes in the Ocular Surface Associated With Dry Eye Disease
NCT00809003 ·Status: COMPLETED
-
Study Evaluating Techniques for Measuring Tear Production
NCT05497479 ·Status: COMPLETED ·Phase: PHASE1
-
Tear Fluid Levels of Loteprednol Etabonate Ophthalmic Gel 0.5% Following a Single Instillation
NCT01736527 ·Status: COMPLETED ·Phase: PHASE1
-
Multicenter Trial Evaluating Quality of Tears Produced by Nasal Neurostimulation
NCT02385292 ·Status: COMPLETED ·Phase: NA
-
Objective Measurements of Prolonged Effects of Restasis on Dry Eye Disease
NCT00567177 ·Status: COMPLETED ·Phase: PHASE4
-
Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time
NCT00760045 ·Status: COMPLETED ·Phase: PHASE2
-
Tear Film Break-Up Time Evaluation of FID 114657
NCT01023464 ·Status: COMPLETED ·Phase: NA
-
iTear Single-center, Open-label, Single-arm Study
NCT06525961 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Evaluation of Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal Spray
NCT05514041 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of Blink Tears and Systane Concomitant With Restasis for the Treatment of Dry Eye Symptoms
NCT00565669 ·Status: COMPLETED ·Phase: NA
-
An Investigation of FID 123320 for the Reduction of Ocular Redness in Pediatric and Adult Populations
NCT06538662 ·Status: COMPLETED ·Phase: PHASE3
-
Study for Remote Investigation of Evaporative Dry Eye Disease
NCT06976515 ·Status: RECRUITING
-
Dermatologic Tacrolimus Ointment on Eyelids in the Treatment of Refractory Vernal Keratoconjunctivitis and Atopic Keratoconjunctivitis
NCT03557203 ·Status: UNKNOWN
-
Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye Disease
NCT03502447 ·Status: TERMINATED ·Phase: NA
-
Study of Efficacy and Tolerability of SYSTANE Complete in Patients With Dry Eye Disease
NCT03492541 ·Status: COMPLETED ·Phase: NA
-
Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye Disease
NCT03597139 ·Status: COMPLETED ·Phase: PHASE2