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To Explore the Functional Connectivity Pattern of Cortical Swallowing Network in the Oral Phase of Post-stroke Dysphagia Based on Dynamic Causal Modelling

NCT06564688 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2024-08-21

No results posted yet for this study

Summary

Swallowing activity in the oral phase is regulated by the cortical swallowing network, and the functional connectivity pattern of the cortical swallowing network is related to swallowing activity. The structural damage of the cortical swallowing network and abnormal activation of brain areas related to swallowing in post-stroke dysphagia affect swallowing activity. The recovery of dysphagia after stroke is related to the compensation of swallowing network in the contralateral hemisphere and different connectivity patterns of diseased brain areas, and the integrity of cortical swallowing network connectivity affects the sequence of oral swallowing activities. However, it is not clear how the functional connectivity patterns and interactions of brain regions of the cortical swallowing network related to oral swallowing activity change in patients with oral dysphagia after stroke.

Conditions

  • Dysphagia After Stroke
  • Cortical Swallowing Network
  • Functional Magnetic Resonance Imaging
  • Oral Phase
  • Dynamic Causal Modelling

Interventions

DIAGNOSTIC_TEST

Swallowing function test

The oral function score assesses the oral functional performance of chewing in all participants. The Functional oral feeding Scale (FOIS) was used to assess the ability of all participants to eat. The standardized swallowing assessment (SSA) was used to assess the global swallowing function of all participants.

Sponsors & Collaborators

  • Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science

    collaborator OTHER_GOV

  • Fujian University of Traditional Chinese Medicine

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-20
Primary Completion
2025-07-01
Completion
2025-07-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06564688 on ClinicalTrials.gov