The Effect of Sedation on Rebound Pain in Knee Arthroplasty
NCT06555458 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 84
Last updated 2024-08-19
Summary
Dexmedetomidine is often used for sedation procedures. It has also been shown to have a pain-protective effect. Researchers predicted that using dexmedetomidine for sedation in total knee arthroplasties performed under spinal anesthesia would reduce the frequency of rebound pain and pain scores.
Conditions
- Total Knee Arthroplasty
- Sedation
Interventions
- DRUG
-
Dexmedetomidine
Patient group to be given dexmedetomidine
- DRUG
-
Saline
Patient group to be given salin
Sponsors & Collaborators
-
Ankara City Hospital Bilkent
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-11-19
- Primary Completion
- 2024-03-30
- Completion
- 2024-07-25
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Dexmedetomidine on Tourniquet Induced -Systemic Effects
NCT04307290 ·Status: COMPLETED ·Phase: PHASE4
-
Intravenous Regional Analgesia of Dexmedetomidine
NCT07131579 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block
NCT03629483 ·Status: TERMINATED ·Phase: PHASE4
-
The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia
NCT02535273 ·Status: UNKNOWN ·Phase: PHASE4
-
Intraoperative Sedatives and Postoperative Pain
NCT02784626 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery
NCT06665438 ·Status: RECRUITING ·Phase: PHASE3
-
Comparison of the Effects of Dexmedetomidine and Ketamine Infusion on the Inflammatory Response in Liver Resection
NCT06219928 ·Status: COMPLETED ·Phase: NA
-
Prevention of Shivering Associated With Spinal Anesthesia
NCT06082076 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia
NCT03322098 ·Status: COMPLETED ·Phase: NA
-
Optimal Single Dose Intrathecal Dexmedetomidine for Postoperative Analgesia
NCT02660658 ·Status: UNKNOWN ·Phase: NA
-
Dexmedetomidine for Improved Pain Relief and Recovery in Spine Surgery
NCT06685081 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine vs Propofol Sedation Reduces Postoperative Delirium in Patients Receiving Hip Arthroplasty.
NCT02793986 ·Status: COMPLETED ·Phase: NA
-
The Effect of Dexmedetomidine on Postoperative Cognitive Function in Geriatric Patients
NCT07047898 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Loading of Midazolam or Dexmedetomidine on Hemodynamics
NCT02634021 ·Status: WITHDRAWN ·Phase: PHASE4
-
Effect of Dexmedetomidine on Hemodynamics in Cardiac Surgery
NCT06958913 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine Dosage for Postoperative Delirium and Cognitive Function in Elderly TKA Patients
NCT06614881 ·Status: COMPLETED ·Phase: NA
-
The Effect of Dexmedetomidine on Postoperative Quality of Recovery
NCT03468062 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
NCT07330375 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Dental Treatment
NCT06097169 ·Status: COMPLETED
-
Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
NCT07214701 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Efficacy of Intravenous Dexketoprofen and Tenoxicam on Propofol Associated Injection Pain
NCT02285972 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine as an Adjuvant for Femoral Nerve Block and Functional Recovery After Total Knee Arthroplasty
NCT04642651 ·Status: COMPLETED ·Phase: PHASE4
-
Intravenous Dexmedetomidine Versus Midazolam in Preventing Shivering in Trauma Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
NCT07300826 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Dexmedetomidine Intra Venous Arthroplasty
NCT03834129 ·Status: COMPLETED ·Phase: PHASE3
-
Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA
NCT06566482 ·Status: RECRUITING ·Phase: PHASE4